Paragonimus infection: Rare manifestation with pericardial effusion: Case report and Literature review

被引:2
作者
Al Bishawi, Ahmad [1 ]
Salameh, Sarah [1 ]
Ehtesham, Ahsan [2 ]
Massad, Ihab [2 ]
Arachchige, Suresh [3 ]
Hatim, Ahmed [3 ]
Bozom, Issam [4 ]
Thapur, Maliha [1 ]
机构
[1] Hamad Med Corp, Dept Internal Med, Div Infect Dis, PO POX 3050, Doha, Qatar
[2] Hamad Med Corp, Dept Surg, Div Cardiothorac Surg, Doha, Qatar
[3] Hamad Med Corp, Dept Internal Med, Div Gen Med, Doha, Qatar
[4] Hamad Med Corp, Dept Clin Lab Med & Pathol, Doha, Qatar
关键词
Paragonimus; Pericardial effusion; Tuberculosis; PULMONARY PARAGONIMIASIS; CLINICAL-FEATURES; PRAZIQUANTEL;
D O I
10.1016/j.idcr.2021.e01075
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Background: Paragonimus, is a globally distributed trematode, with human disease limited to endemic regions. It can be transmitted to humans through ingestion of intermediate hosts that are crustaceans. Most symptomatic infections consist of pulmonary disease, and in aberrant migration of immature flukes, extrapulmonary manifestations may occur. These presentations are relatively uncommon and may affect various organs with atypical Clinico-radiological pathologies that are often challenging to diagnose. Pericardial involvement has scarcely been reported before. Furthermore, the management, clinical outcomes and potential complications of this involvement remain unclear. Case report: Our patient is a 31-year-old Nepalese male who presented with abdominal distension and lower limb oedema. Initial work up revealed pericardial effusion, and analysis was suggestive of exudative lymphocytic effusion. Supported by positive QuantiFERON result along with his demographic data, the patient was treated presumptively as a case of tuberculous pericarditis, despite the negative initial Mycobacterial Tuberculosis work up. During follow up, the patient lacked clinical response and repeated echocardiography showed signs of tamponade with concomitant pleural effusion. subsequently video-assisted-thoracoscopy pericardial window along with pericardial and pleural biopsy were performed. Histopathological examination of the biopsied tissue revealed non-necrotizing granulomas containing a parasitic egg suggestive of Paragonimus. Fortunately, the patient received treatment with praziquantel and subsequently made good clinical recovery. Conclusion: Diagnosis of extrapulmonary Paragonimus infection can be challenging given its rarity and clinical picture mimicking other infectious aetiologies. Pericardial involvement is seldom reported in the literature and clinical suspicion should be raised particularly when dealing with atypical presentations and relevant demographic data. (C) 2021 The Author(s). Published by Elsevier Ltd.
引用
收藏
页数:6
相关论文
共 19 条
[1]   A case of group infections with Paraginimus species in Henan, Central China [J].
Chen, Wei-qi ;
Deng, Yan ;
Zhang, Ya-lan ;
Ai, Lin ;
Chen, Jia-xu ;
Lin, Xi-meng ;
Du, Xiao-bo ;
Li, Peng ;
Zhou, Rui-min ;
Yang, Cheng-yun ;
Liu, Ying ;
Zhang, Hong-wei ;
Xu, Bian-li ;
Zhao, Yu-ling .
ACTA TROPICA, 2020, 202
[2]  
Gong Z, 2017, MED US, V96
[3]  
JOHNSON RJ, 1985, REV INFECT DIS, V7, P200
[4]   Role of QuantiFERON-TB Gold, Interferon Gamma Inducible Protein-10 and Tuberculin Skin Test in Active Tuberculosis Diagnosis [J].
Kabeer, Basirudeen Syed Ahamed ;
Raman, Balambal ;
Thomas, Aleyamma ;
Perumal, Venkatesan ;
Raja, Alamelu .
PLOS ONE, 2010, 5 (02)
[5]   Paragonimus westermani infection manifesting as a pulmonary cavity and adrenal gland mass: A case report [J].
Kwon, Yong Shik ;
Lee, Hye Won ;
Kim, Hyun Jung .
JOURNAL OF INFECTION AND CHEMOTHERAPY, 2019, 25 (03) :200-203
[6]   Paragonimus kellicotti Fluke Infections in Missouri, USA [J].
Lane, Michael A. ;
Marcos, Luis A. ;
Onen, Nur F. ;
Demertzis, Lee M. ;
Hayes, Ericka V. ;
Davila, Samuel Z. ;
Nurutdinova, Diana R. ;
Bailey, Thomas C. ;
Weil, Gary J. .
EMERGING INFECTIOUS DISEASES, 2012, 18 (08) :1263-1267
[7]   Paragonimiasis: an important food-borne zoonosis in China [J].
Liu, Quan ;
Wei, Feng ;
Liu, Wensen ;
Yang, Songtao ;
Zhang, Xichen .
TRENDS IN PARASITOLOGY, 2008, 24 (07) :318-323
[8]   Paragonimiasis in Japan: A Twelve-year Retrospective Case Review (2001-2012) [J].
Nagayasu, Eiji ;
Yoshida, Ayako ;
Hombu, Amy ;
Horii, Yoichiro ;
Maruyama, Haruhiko .
INTERNAL MEDICINE, 2015, 54 (02) :179-186
[9]   Can Pleuropulmonary Paragonimiasis be Cured by Only the 1st Set of Chemotherapy? Treatment Outcome and Clinical Features of Recently Developed Pleuropulmonary Paragonimiasis [J].
Oh, In-Jae ;
Kim, Yu-Il ;
Chi, Su-Young ;
Ban, Hee-Jung ;
Kwon, Yong-Soo ;
Kim, Kyu-Sik ;
Kim, Young-Chul ;
Kim, Yun-Hyeon ;
Seon, Hyun Ju ;
Lim, Sung-Chul ;
Shin, Hee-Young ;
Kim, Soo-Ock .
INTERNAL MEDICINE, 2011, 50 (13) :1365-1370
[10]  
SABORIO P, 1995, J TROP MED HYG, V98, P316