Extramedullary nasal plasmacytoma arising after polyp excision and the role of the inflammation in tumor development: A case report

被引：4

作者：

Di Stadio, Arianna ^{[1
]}

Gambacorta, Valeria ^{[1
]}

De Crescenzo, Stefano ^{[2
]}

Sidoni, Angelo ^{[2
]}

Cristi, Maria Cristina ^{[3
]}

Di Giovanni, Alfredo ^{[1
]}

Maranzano, Massimo ^{[4
]}

Ricci, Giampietro ^{[1
]}

机构：

[1] Univ Perugia, Dept Otolaryngol, Piazza Menghini 1, I-65121 Perugia, Italy

[2] Univ Perugia, Dept Anat Pathol, I-65121 Perugia, Italy

[3] Silvestrini Hosp, Dept Otolaryngol, I-65121 Perugia, Italy

[4] Univ Manchester, Dept Oral Maxillofacial & Facial Plast Surg, Manchester M13 9PL, Lancs, England

来源：

MOLECULAR AND CLINICAL ONCOLOGY | 2020年 / 12卷 / 05期

关键词：

extramedullary nasal plasmacytoma; polyp; nasal obstruction; surgery; inflammation; tumorigenesis; EPSTEIN-BARR-VIRUS; MULTIPLE-MYELOMA; CAVITY; HEAD;

D O I：

10.3892/mco.2020.2007

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A correlation between inflammation and cancer has been identified in the case of nasal cancer, however a specific connection between nasal inflammation and extramedullary nasal plasmacytoma (ENP), to the best of our knowledge, has not yet been determined. The present case report describes a patient affected by ENP, in who the tumor arose in the same area, from which a nasal polyp was previously surgically removed, five months after the polyp excision. The patient underwent surgical endoscopic tumor asportation without being treated with radio-chemotherapy. ENP was totally removed via surgery and no signs of recurrence were identified by endoscopy or magnetic resonance imaging during the last check-up 1 year after tumor asportation. It was hypothesized that in this elderly patient, who was exposed to viral infections and pollution for several years, ENP may be correlated to the inflammatory process that occurred after surgery, and this likely contributed to a neoplastic mutation in B-cells.

引用

页码：451 / 455

页数：5

共 26 条

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