Carcinoid Heart Disease: a Comprehensive Review

被引:14
作者
Hassan, Saamir A. [1 ]
Palaskas, Nicolas L. [1 ]
Agha, Ali M. [1 ]
Iliescu, Cezar [1 ]
Lopez-Mattei, Juan [1 ]
Chen, Christopher [2 ]
Zheng, Henry [2 ]
Yusuf, Syed Wamique [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Cardiol, Div Med, Houston, TX 77030 USA
[2] Baylor Coll Med, Dept Med, Houston, TX 77030 USA
关键词
Carcinoid heart disease; Multimodality imaging; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; NEUROENDOCRINE TUMORS; VALVE-REPLACEMENT; TRICUSPID-VALVE; CORONARY SPASM; CARDIAC-ARREST; SEROTONIN; PROGRESSION; LANREOTIDE; MANAGEMENT;
D O I
10.1007/s11886-019-1207-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of Review Carcinoid heart disease is a rare disorder that is associated with significant morbidity and mortality. In this review of the literature, we will present current concepts in diagnosis and management of carcinoid heart disease. Recent Findings Recent expert consensus guidelines highlight the role of echocardiography and screening with NT-proBNP for the evaluation of carcinoid heart disease. Advances in medical therapy along with better surgical outcomes highlight the experience and expertise that has been gained in the treatment of carcinoid heart disease. Summary Carcinoid heart disease occurs in patients with neuroendocrine tumors who have carcinoid syndrome. Serotonin appears to play a central role in the development of carcinoid heart disease. Cardiac biomarkers and multimodality imaging can be used to aid in screening and diagnosis. The mainstay of treatment of carcinoid heart disease is surgery.
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页数:7
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