Seroprevalence of viral hepatitis in Tanzanian adults

被引:0
|
作者
Miller, WC
Shao, JF
Weaver, DJ
Shimokura, GH
Paul, DA
Lallinger, GJ
机构
[1] Univ N Carolina, Dept Epidemiol, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Dept Med, Chapel Hill, NC 27599 USA
[3] Kilimanjaro Christian Med Ctr, Moshi, Tanzania
[4] Campbell Univ, Dept Biol, Buies Creek, NC 27506 USA
[5] Abbott Labs, Expt Biol Res, N Chicago, IL 60064 USA
[6] Duke Univ, Med Ctr, Div Infect Dis & Int Hlth, Durham, NC USA
关键词
viral hepatitis; seroprevalence; hepatitis A; hepatitis B; hepatitis C; hepatitis E; Tanzania; Africa;
D O I
暂无
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
In a cross-sectional study in Dar es Salaam, Tanzania, we determined the seroprevalence of markers for hepatitis A, B, C and E viruses and examined associated risk markers. Among 403 healthy adults, the seroprevalence of antibodies to hepatitis A virus was 99.0% (95% confidence interval: 97.5-99.7). Prior exposure to hepatitis C and E viruses was rare (hepatitis C: 0.7% (0.2-2.1); hepatitis E: 0.2% (< 0.1-1.4)). The prevalence of all markers of hepatitis B was 70.7% (66.0-75.1). Hepatitis B surface antigen was identified in 6.0% (3.9-8.7) of subjects. Independent predictors of hepatitis B infection identified by logistic regression included older age, male gender, Muslim religion and type of abode. Given the high prevalence of hepatitis B and the low prevalence of hepatitis C, the majority of chronic viral hepatitis is likely to be associated with hepatitis B. Control efforts should focus primarily on hepatitis B.
引用
收藏
页码:757 / 763
页数:7
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