Blockage of longitudinal flow in Meniere's disease: A human temporal bone study

被引：16

作者：

Shimizu, Shigetaka ^{[2
]}

Cureoglu, Sebahattin ^{[1
]}

Yoda, Shigetoshi ^{[3
]}

Suzuki, Mamoru ^{[2
]}

Paparella, Michael M. ^{[4
]}

机构：

[1] Univ Minnesota, Dept Otolaryngol, Minneapolis, MN 55455 USA

[2] Tokyo Med Univ, Dept Otolaryngol, Tokyo, Japan

[3] Kawasaki Med Sch, Dept Otolaryngol, Kurashiki, Okayama, Japan

[4] Paparella Ear Head & Neck Inst, Minneapolis, MN USA

来源：

ACTA OTO-LARYNGOLOGICA | 2011年 / 131卷 / 03期

关键词：

Histopathology; endolymphatic hydrops; endolymphatic duct; utriculo-endolymphatic valve; ductus reuniens; fistula; UTRICULO-ENDOLYMPHATIC VALVE; PATHOGENESIS; DUCT;

D O I：

10.3109/00016489.2010.532155

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Conclusion: Blockage of the endolymphatic duct is a significant finding in Meniere's disease. The position of the utriculo-endolymphatic valve (UEV) and blockage of the ductus reuniens in the temporal bones were not found to be directly indicative of Meniere's disease. Objective: Comparison of blockage of the longitudinal flow of endolymph between ears affected by Meniere's disease and normal ears. Methods: We examined 21 temporal bones from 13 subjects who had Meniere's disease and 21 normal temporal bones from 12 controls. Results: The endolymphatic duct was blocked in five (23%) ears affected by Meniere's disease (p = 0.016). The utricular duct was blocked in 16 (76%) ears affected by Meniere's disease and 11 (52%) normal ears (p = 0.112). The saccular duct was blocked in 6 (28%) of ears affected by Meniere's disease and 16 (76%) normal ears (p = 0.001). The ductus reuniens was blocked in 10 (47%) ears affected by Meniere's disease and 10 (47%) normal ears (p = 1.000).

引用

页码：263 / 268

页数：6

共 15 条

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