Biopsy examination of squamous cell carcinoma of the tongue: Source of significant prognostic information?

被引：8

作者：

Moor, J. W. ^{[2
]}

Wills, S. ^{[3
]}

Holzle, F. ^{[4
]}

Ong, T. K. ^{[6
]}

Mitchell, D. A. ^{[7
]}

MacLennan, K. A. ^{[5
]}

Kanatas, A. N. ^{[1
]}

机构：

[1] Leeds Dent Inst, Oral & Maxillofacial Dept, Leeds LS2 9LU, W Yorkshire, England

[2] Leeds Gen Infirm, Dept Otolaryngol Head & Neck Surg, Leeds LS1 3EX, W Yorkshire, England

[3] Leeds Gen Infirm, Dept Histopathol, Leeds LS1 3EX, W Yorkshire, England

[4] Tech Univ Munich, Dept Oral & Maxillofacial Surg, Klinikum Rechts Isar, D-81675 Munich, Germany

[5] St James Univ Hosp, Canc Res UK, Leeds LS9 7TF, W Yorkshire, England

[6] Leeds Gen Infirm, Leeds LS2 9LU, W Yorkshire, England

[7] Pinderfields Gen Hosp, Oral & Facial Specialties Dept, Wakefield WF1 4DG, England

来源：

BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY | 2010年 / 48卷 / 08期

关键词：

Tongue biopsy; Squamous cell carcinoma of the tongue; Prognostic information and squamous cell carcinoma; Head and neck cancer; CERVICAL NODE METASTASES; TUMOR THICKNESS; ORAL-CAVITY; CANCER; NECK; PARAMETERS; FEATURES; T1;

D O I：

10.1016/j.bjoms.2009.12.003

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Histological analysis of tumour resection for squamous cell carcinoma (SCC) of the tongue yields prognostic information. We analysed histological slides of biopsy and tumour resection specimens using an adapted malignancy grading score and analysed variables of neck dissections. There was moderate correlation between biopsy and tumour resection using malignancy grading scores (correlation coefficient 0.45); good agreement of tumour grade (79%), tumour depth (76%), and type of invasive front (80%), but correlation was only fair to moderate (kappa =0.38, kappa = 0.51, and kappa = 0.41, respectively). Correlation of the biopsy grading score and invaded nodes in the neck, extra capsular spread, and soft tissue disease was not significant. (C) 2009 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

引用

页码：594 / 597

页数：4

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