Leg bone pain syndrome in a patient with ulcerative colitis treated with cyclosporin

Background Leg bone pain syndrome is an unusual condition associated with the use of calcineurin antagonists, initially described in patients receiving allograft transplantation. Aim To describe the first known reported case of leg bone pain syndrome in a patient with ulcerative colitis receiving cyclosporin. Results Investigations revealed no diagnostic features. Calcium channel blocker was used successfully in the treatment of this condition. Conclusion In the absence of diagnostic investigations, a high index of clinical suspicion is needed to diagnose and successfully manage leg bone pain syndrome. This may prevent further complications such as osteonecrosis that may arise.