Two Types of Polyp Shape Observed in the Stomach of Patients with Peutz-Jeghers Syndrome

被引:0
作者
Iwamuro, Masaya [1 ]
Toyokawa, Tatsuya [3 ]
Matsueda, Kazuhiro [4 ]
Hori, Shinichiro [5 ]
Yoshioka, Masao [6 ]
Moritou, Yuki [7 ]
Tanaka, Takehiro [2 ]
Mizuno, Motowo [4 ]
Okada, Hiroyuki [1 ]
机构
[1] Okayama Univ, Dept Gastroenterol & Hepatol, Grad Sch Med Dent & Pharmaceut Sci, Okayama 7008558, Japan
[2] Okayama Univ, Dept Pathol, Grad Sch Med Dent & Pharmaceut Sci, Okayama 7008558, Japan
[3] Fukuyama Med Ctr, Dept Gastroenterol, Fukuyama, Hiroshima 7208520, Japan
[4] Kurashiki Cent Hosp, Dept Gastroenterol & Hepatol, Okayama 7108602, Japan
[5] Shikoku Canc Ctr, Dept Endoscopy, Matsuyama, Ehime 7910280, Japan
[6] Okayama Saiseikai Gen Hosp, Dept Internal Med, Okayama 7008511, Japan
[7] Hiroshima City Hiroshima Citizens Hosp, Dept Internal Med, Hiroshima 7308518, Japan
关键词
Peutz-Jeghers syndrome; esophagogastroduodenoscopy; gastric polyps; CANCER; MANAGEMENT; UPDATE; STK11;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The characteristics of gastric polyps in patients with Peutz-Jeghers (PJ) syndrome (PJS) have not been fully investigated. The objective of this study was to reveal the endoscopic and pathologic findings of gastric polyps in patients with PJS. We reviewed 11 patients with PJS treated at 6 institutions, and summarized the endoscopic and pathologic features of their gastric polyps. The polyps were mainly classified into 2 types: (i) solitary or sporadic polyps > 5 mm, reddish in color with a sessile or semi-pedunculated morphology (n = 9); and (ii) multiple sessile polyps <= 5 mm with the same color tone as the peripheral mucosa (n = 9). Patients who underwent endoscopic mucosal resection for polyps > 5 mm were diagnosed with PJ polyps (n = 2), whereas those who underwent biopsy were diagnosed with hyperplastic polyps. Polyps <= 5 mm were pathologically diagnosed as fundic gland polyps or hyperplastic polyps. This study revealed that patients with PJS present with 2 types of polyps in the stomach. Endoscopic mucosal resection of polyps > 5 mm seems necessary for the pathologic diagnosis of PJ polyps.
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收藏
页码:471 / 477
页数:7
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