Soft Tissue Special Issue: Gnathic Fibro-Osseous Lesions and Osteosarcoma

被引:20
作者
Hameed, Meera [1 ]
Horvai, Andrew E. [2 ]
Jordan, Richard C. K. [2 ]
机构
[1] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10065 USA
[2] Univ Calif San Francisco, San Francisco, CA 94143 USA
关键词
Fibro-osseous lesions; Ossifying fibroma; Cemento-ossifying fibroma; Juvenile trabecular ossifying fibroma; Juvenile psammomatoid ossifying fibroma; Cemento-osseous dysplasia; Diffuse sclerosing osteomyelitis; Fibrous dysplasia; Osteosarcoma; JUVENILE OSSIFYING FIBROMA; MCCUNE-ALBRIGHT SYNDROME; DIFFUSE SCLEROSING OSTEOMYELITIS; CEMENTO-OSSEOUS DYSPLASIA; SAPHO SYNDROME; JAW; MUTATION; HRPT2; BONE; GENE;
D O I
10.1007/s12105-019-01094-2
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Gnathic fibro-osseous lesions are a diverse group of disease processes which share overlapping microscopic features characterized by fibroblastic stroma with variable cellularity and a range of bone forming pathological processes leading to woven, sclerotic and cementum-like structures. Some of the lesions are unique to craniofacial location and a combination of clinical, radiological and pathological correlation is often necessary for diagnostic accuracy. Gnathic osteosarcomas are rare tumors with differences in age distribution and behavior as compared to osteosarcoma of long bones. This review will discuss the clinicopathological and radiological features of gnathic fibro-osseous lesions and osteosarcoma with updates on current genetics and molecular pathogenesis.
引用
收藏
页码:70 / 82
页数:13
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