Screening for Aphasia in NeuroDegeneration for the Diagnosis of Patients with Primary Progressive Aphasia: Clinical Validity and Psychometric Properties

被引：18

作者：

Battista, Petronilla ^{[1
,2
,3
]}

Catricala, Eleonora ^{[4
]}

Piccininni, Marco ^{[1
,2
]}

Copetti, Massimiliano ^{[5
]}

Esposito, Valentina ^{[6
,7
,8
]}

Polito, Cristina ^{[3
]}

Miozzo, Antonio ^{[9
]}

Gobbi, Elena ^{[8
,13
]}

Cuoco, Sofia ^{[10
]}

Boschi, Veronica ^{[4
]}

Picillo, Marina ^{[10
]}

Sorbi, Sandro ^{[3
,11
]}

Barone, Paolo ^{[10
]}

Iannaccone, Sandro ^{[6
,7
]}

Garrard, Peter ^{[12
]}

Logroscino, Giancarlo ^{[1
,2
]}

Cappa, Stefano F. ^{[13
]}

机构：

[1] Univ Bari Aldo Moro, Dept Basic Med Sci Neurosci & Sense Organs, Bari, Italy

[2] Univ Bari Aldo Moro, Neurodegenerat Dis Unit, Dept Clin Res Neurol, Pia Fdn Cardinale G Panico, Tricase, Italy

[3] Univ Firenze, NEUROFARBA Dipartimento Neurosci Psicol Area Farm, Florence, Italy

[4] Scuola Univ Super IUSS Pavia, Ctr Neurocognit & Theoret Syntax, Pavia, Italy

[5] IRCCS Osped Casa Sollievo Sofferenza, Biostat Unit, San Giovanni Rotondo, Italy

[6] IRCCS San Raffaele Hosp, Dept Specialist Rehabil Neurol Cognit & Motor Dis, Milan, Italy

[7] Univ Vita Salute San Raffaele, Milan, Italy

[8] Univ Vita Salute San Raffaele, Milan, Italy

[9] Univ Brescia, Dept Clin & Expt Sci, Brescia, Italy

[10] Univ Salerno, Dipartimento Med & Chirurg, Salerno, Italy

[11] IRCCS Don Gnocchi Firenze, Florence, Italy

[12] St Georges Univ London, Neurosci Res Ctr, London, England

[13] IRCCS S Giovanni Dio Fatebenefratelli, Brescia, Italy

来源：

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS | 2018年 / 46卷 / 3-4期

关键词：

Language impairment; Screening instrument; Dementia; Diagnostic accuracy; Speech-language assessment; IMPAIRMENT; CRITERIA; TESTS;

D O I：

10.1159/000492632

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Background: We evaluated the psychometric proprieties of the Screening for Aphasia in NeuroDegeneration (SAND) battery in Italian primary progressive aphasia (PPA) and movement disorder (MD) patients. Methods: The sample included 30 consecutive PPA and 45 MD patients who completed the SAND battery together with a clinical interview and a neurological/neuropsychological examination and 130 healthy controls (HC). Results: The SAND battery showed good internal consistency and good convergent and divergent validity. receiver operating characteristic analysis revealed an area under the curve of 0.978 for PPA versus HC and of 0.786 for PPA versus MD. A cutoff 3 gave a sensitivity of 0.933% and a specificity of 0.946% for discriminating PPA versus HC, whereas a cutoff 5 gave a sensitivity of 0.767% and a specificity of 0.667% for discriminating PPA versus MD. Conclusion: These results indicate that the SAND battery is an adequate, reliable, and valid diagnostic tool for PPA. (C) 2018 S. Karger AG, Basel

引用

页码：243 / 252

页数：10

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