Occurrence and clinical features of viral hepatitis C in hemophilia children.

被引：0
|
作者：
Yatsenko, EA [1 ]
Mazurin, AV [1 ]
Yakunina, LN [1 ]
Reizis, AR [1 ]
Plakhuta, TG [1 ]
Soskov, GI [1 ]
Vdovin, VV [1 ]
Shipulin, GA [1 ]
机构：
[1] Res Inst Pediat Hematol, Moscow, Russia
来源：
GEMATOLOGIYA I TRANSFUZIOLOGIYA | 2001年 / 46卷 / 01期
关键词：
children; hemophilia; hepatitis C; hemostatic therapy;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
115 children with hemophilia A and B aged 2 to 17 years living in Moscow or Moscow Region were examined for hepatitis C infection. Families of the examinees had poor knowledge of HCV infection sequelae. HCV infection was found in 55.8-40.5% of the children depending on the number of transfusions and duration of the symptoms. Posttransfusion hepatitis C in children with hemophilia is characterized by latent course, The treatment of chronic hepatitis C consisted of intramuscular injections of roferon A (3 000 000 IU 3 times a day). Maintenance of hemostasis at the level 20-30% allows conduction of interferon treatment for 12-18 months without hemorrhagic complications.
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收藏
页码：28 / 29
页数：2
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