Addressing a vascular endothelium array with blood components using underlying microfluidic channels

被引：53

作者：

Genes, Luiza I. ^{[1
]}

Tolan, Nicole V.

Hulvey, Matthew K.

Martin, R. Scott

Spence, Dana M.

机构：

[1] Michigan State Univ, Dept Chem, E Lansing, MI 48824 USA

[2] St Louis Univ, Dept Chem, St Louis, MO 63103 USA

来源：

LAB ON A CHIP | 2007年 / 7卷 / 10期

关键词：

D O I：

10.1039/b712619k

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Here, we show that an array of endothelial cells, addressable by an underlying microfluidic network of channels containing red blood cells, can be employed as an in vitro model of in vivo circulation to monitor cellular communication between different cell types in the drug discovery process.

引用

页码：1256 / 1259

页数：4

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