Survival with nonmelanoma skin cancer in Germany

被引:69
作者
Eisemann, N. [1 ]
Jansen, L. [3 ]
Castro, F. A. [3 ]
Chen, T. [4 ]
Eberle, A. [6 ]
Nennecke, A. [7 ]
Zeissig, S. R. [8 ]
Brenner, H. [3 ,5 ,9 ,10 ]
Katalinic, A. [1 ,2 ]
机构
[1] Med Univ Lubeck, Inst Social Med & Epidemiol, Ratzeburger Allee 160, D-23562 Lubeck, Germany
[2] Med Univ Lubeck, Inst Canc Epidemiol, Ratzeburger Allee 160, D-23562 Lubeck, Germany
[3] German Canc Res Ctr, Div Clin Epidemiol & Aging Res, D-69120 Heidelberg, Germany
[4] German Canc Res Ctr, Div Mol Genet Epidemiol C050, D-69120 Heidelberg, Germany
[5] German Canc Res Ctr, German Canc Consortium DKTK, D-69120 Heidelberg, Germany
[6] Canc Registry Bremen, Achterstr 30, D-28359 Bremen, Germany
[7] Canc Registry Hamburg, Billstr 80, D-20539 Hamburg, Germany
[8] Canc Registry Rhineland Palatinate, Obere Zahlbacher Str 69, D-55131 Mainz, Germany
[9] German Canc Res Ctr, Div Prevent Oncol, INF 460, D-69120 Heidelberg, Germany
[10] Natl Ctr Tumor Dis NCT, INF 460, D-69120 Heidelberg, Germany
关键词
VITAMIN-D; MORTALITY; POPULATION; TRENDS;
D O I
10.1111/bjd.14352
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background Nonmelanoma skin cancer (NMSC) is the most common cancer in Germany, but detailed information on survival is lacking. Objectives To provide survival estimates for female and male patients with basal cell carcinoma (BCC), squamous cell carcinoma (SCC), sarcoma, adenocarcinoma and Merkel cell carcinoma. Further subgroup analyses were carried out by age, tumour stage and body site. Methods In total 459 640 patients diagnosed with NMSC in 1997-2011 were included from population-based cancer registers, covering a population of 33 million inhabitants. Age-standardized absolute and relative 5-year and 10-year survival were calculated using period analysis. Results The absolute and relative 5-year survival were 87.1% and 102.9% for BCC, 77.6% and 93.6% for SCC, 82.1% and 96.0% for sarcoma, 71.4% and 85.7% for adenocarcinoma and 60.0% and 70.7% for Merkel cell carcinoma, respectively. Higher age, female sex and advanced stage were associated with lower survival. Conclusions A comprehensive overview of NMSC survival in Germany is provided. The differences between the NMSC subtypes require a more differentiated consideration of patient survival. The survival advantage of patients with BCC may be related to health-promoting factors related to the BCC diagnosis, such as changes to a healthier lifestyle.
引用
收藏
页码:778 / 785
页数:8
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