1,1-disubstituted tetrahydroisoquinolines from enaminones via Pictet-Spengler reaction

被引：10
|
作者：
Venkov, AP [1 ]
Angelov, PA [1 ]
机构：
[1] Paisij Hilendarski Univ Plovdiv, Dept Organ Chem, BG-4000 Plovdiv, Bulgaria
来源：
SYNTHETIC COMMUNICATIONS | 2003年 / 33卷 / 17期
关键词：
enaminones; tetrahydroisoquinolines; cyclization; Pictet-Spengler reaction;
D O I：
10.1081/SCC-120022477
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Enaminones, prepared by condensation of homoveratrylamine with 1,3-dicarbonyl compounds, undergo intramolecular cyclization in acidic media to afford 1,1-disubstituted tetrahydroisoquinolines in good yields. Further modification of the title compounds is demonstrated.
引用
收藏
页码：3025 / 3033
页数：9
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