Auditory event-related potentials in Parkinson's disease: Prominent correlation with attention

被引:22
|
作者
Matsui, Hideaki [1 ]
Nishinaka, Kazuto [1 ]
Oda, Masaya [1 ]
Kubori, Tamotsu [1 ]
Udaka, Fukashi [1 ]
机构
[1] Sumitomo Hosp, Dept Neurol, Kita Ku, Osaka 5300005, Japan
关键词
Parkinson's disease; dementia; auditory event-related potentials; P300; attention;
D O I
10.1016/j.parkreldis.2006.12.012
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: Auditory P300 has been reported to be abnormal in demented patients with Parkinson's disease. However, it is still controversial which factors in Parkinson's disease influence P300 parameters. Methods: Forty patients with Parkinson's disease were included. Patients were divided into two groups: patients with dementia (PDD) and without dementia (PDND). An `odd-ball' paradigm was used for auditory event-related potentials. Results: P300 latency was markedly delayed in PDD patients. Age and DRSI (attention) were the most important factors influencing P300 latency. Conclusions: Although there have been reports of P300 in the past, its abnormalities reflect the deficit of attention in Parkinson's disease. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:394 / 398
页数:5
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