Overcoming the demons of protecting groups with amphoteric molecules

被引：1

作者：

Yudin, Andrei K. ^{[1
]}

Hili, Ryan ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem, Davenport Res Labs, Toronto, ON M5S 3H6, Canada

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2007年 / 13卷 / 23期

关键词：

amino aldehydes; amphoteric molecules; chemoselectivity; organic synthesis; protecting groups;

D O I：

10.1002/chem.200700710

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthetic organic chemists have long depended on protecting group manipulations when faced with the challenges of chemoselectivity and functional group incompatibility. Overcoming this dependence will improve the overall efficiency of chemical synthesis. By taking advantage of orthogonally reactive functional groups, amphoteric molecules can afford access not only to more efficient and strategic syntheses but also to the development of novel chemical transformations.

引用

页码：6539 / 6542

页数：4

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