Open label phase 1b/2 study of ladiratuzumab vedotin in combination with pembrolizumab for first-line treatment of patients with unresectable locally-advanced or metastatic triple-negative breast cancer

被引：46

作者：

Han, Hyo ^{[1
]}

Diab, Sami ^{[2
]}

Alemany, Carlos ^{[3
]}

Basho, Reva ^{[4
]}

Brown-Glaberman, Ursa ^{[5
]}

Meisel, Jane ^{[6
]}

Pluard, Timothy ^{[7
]}

Cortes, Javier ^{[8
,9
,10
]}

Dillon, Patrick ^{[11
]}

Ettl, Johannes ^{[12
]}

Kuemmel, Sherko ^{[13
]}

Sanchez, Luis Manso ^{[14
]}

Oliveira, Mafalda ^{[15
]}

O'Shaughnessy, Joyce ^{[16
]}

Papish, Steven ^{[17
]}

Sinha, Rajni ^{[18
]}

Sterrenberg, Danielle ^{[19
]}

Stringer-Reasor, Erica ^{[20
]}

Tsai, Michaela ^{[21
]}

Vazquez, Rafael Villanueva ^{[22
]}

Wuerstlein, Rachel ^{[23
]}

Wang, Yinghui ^{[24
]}

Wang, Zejing ^{[24
]}

Boni, Valentina ^{[25
]}

机构：

[1] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[2] US Oncol Denver, Denver, CO USA

[3] Canc Inst Florida, Tampa, FL USA

[4] Cedars Sinai Med Ctr, Los Angeles, CA 90048 USA

[5] New Mexico Canc Care Alliance, Albuquerque, NM USA

[6] Winship Canc Inst, Atlanta, GA USA

[7] St Lukes Canc Inst, Kansas City, MO USA

[8] Quiron Grp, IOB Inst Oncol, Madrid, Spain

[9] Quiron Grp, IOB Inst Oncol, Barcelona, Spain

[10] Vall dHebron Inst Oncol VHIO, Barcelona, Spain

[11] Univ Virginia, Charlottesville, VA USA

[12] Tech Univ Munich, Dept Obsteter & Gynecol, Klinikum Rechts Isar, Munich, Germany

[13] Klinikum Essen Mitte, Essen, Germany

[14] Hosp Univ 12 Octubre, Madrid, Spain

[15] Hosp Univ Vall dHebron, Barcelona, Spain

[16] Texas Oncol Sammons Canc Ctr, Dallas, TX USA

[17] Summit Med Grp, Berkeley Hts, NJ USA

[18] Piedmont Canc Inst, Atlanta, GA USA

[19] Ingalls Canc Care, Harvey, IL USA

[20] Univ Alabama Birmingham, Birmingham, AL USA

[21] Virginia Piper Canc Inst, Minneapolis, MN USA

[22] Inst Catala Oncol, Lhospitalet De Llobregat, Spain

[23] Klinikum Univ Munchen, Munich, Germany

[24] Seattle Genet Inc, Bothell, WA USA

[25] START Madrid CIOCC Hosp Univ HM Sanchinarro, Madrid, Spain

来源：

CANCER RESEARCH | 2020年 / 80卷 / 04期

关键词：

D O I：

10.1158/1538-7445.SABCS19-PD1-06

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

PD1-06

引用

页数：3