The Actin Cortex: A Bridge between Cell Shape and Function

被引:91
作者
Chalut, Kevin J. [1 ]
Paluch, Ewa K. [2 ,3 ]
机构
[1] Univ Cambridge, Wellcome Trust Med Res Council Stem Cell Inst, Cambridge CB2 1QR, England
[2] UCL, MRC LMCB, London WC1E 6BT, England
[3] UCL, Inst Phys Living Syst, London WC1E 6BT, England
基金
英国医学研究理事会; 英国生物技术与生命科学研究理事会;
关键词
D O I
10.1016/j.devcel.2016.09.011
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The cortical actin network controls many animal cell shape changes by locally modulating cortical tension. Recent work has provided insight into cortex components and regulators. However, how the network is reorganized in response to cellular signaling, and the role reorganization may play during cell state changes, remain to be determined.
引用
收藏
页码:571 / 573
页数:3
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