Atheroprotective signaling mechanisms activated by steady laminar flow in endothelial cells

被引:114
作者
Berk, Bradford C. [1 ,2 ]
机构
[1] Univ Rochester, Sch Med & Dent, Dept Med, Rochester, NY 14642 USA
[2] Univ Rochester, Sch Med & Dent, Aab Cardiovas Res Inst, Rochester, NY 14642 USA
关键词
antioxidants; atherosclerosis; blood flow; endothelium; inflammation;
D O I
10.1161/CIRCULATIONAHA.107.720730
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:1082 / 1089
页数:8
相关论文
共 92 条
  • [11] Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathways
    Davis, ME
    Cai, H
    Drummond, GR
    Harrison, DG
    [J]. CIRCULATION RESEARCH, 2001, 89 (11) : 1073 - 1080
  • [12] Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Kruppel-like factor (KLF2)
    Dekker, RJ
    van Soest, S
    Fontijn, RD
    Salamanca, S
    de Groot, PG
    VanBavel, E
    Pannekoek, H
    Horrevoets, AJG
    [J]. BLOOD, 2002, 100 (05) : 1689 - 1698
  • [13] Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes
    Dekker, RJ
    van Thienen, JV
    Rohlena, J
    de Jager, SC
    Elderkamp, YW
    Seppen, J
    de Vries, CJM
    Biessen, EAL
    van Berkel, TJC
    Pannekoek, H
    Horrevoets, AJG
    [J]. AMERICAN JOURNAL OF PATHOLOGY, 2005, 167 (02) : 609 - 618
  • [14] VASCULAR ENDOTHELIUM RESPONDS TO FLUID SHEAR-STRESS GRADIENTS
    DEPAOLA, N
    GIMBRONE, MA
    DAVIES, PF
    DEWEY, CF
    [J]. ARTERIOSCLEROSIS AND THROMBOSIS, 1992, 12 (11): : 1254 - 1257
  • [15] JNK1 - A PROTEIN-KINASE STIMULATED BY UV-LIGHT AND HA-RAS THAT BINDS AND PHOSPHORYLATES THE C-JUN ACTIVATION DOMAIN
    DERIJARD, B
    HIBI, M
    WU, IH
    BARRETT, T
    SU, B
    DENG, TL
    KARIN, M
    DAVIS, RJ
    [J]. CELL, 1994, 76 (06) : 1025 - 1037
  • [16] In vivo induction of endothelial apoptosis leads to vessel thrombosis and endothelial denudation - A clue to the understanding of the mechanisms of thrombotic plaque erosion
    Durand, E
    Scoazec, A
    Lafont, A
    Boddaert, J
    Al Hajzen, A
    Addad, F
    Mirshahi, M
    Desnos, M
    Tedgui, A
    Mallat, Z
    [J]. CIRCULATION, 2004, 109 (21) : 2503 - 2506
  • [17] Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent
    Galkina, Elena
    Kadl, Alexandra
    Sanders, John
    Varughese, Danielle
    Sarembock, Ian J.
    Ley, Klaus
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2006, 203 (05) : 1273 - 1282
  • [18] Flow antagonizes TNF-α signaling in endothelial cells by inhibiting caspase-dependent PKCζ processing
    Garin, Gwenaele
    Abe, Jun-Ichi
    Mohan, Amy
    Lu, Weimin
    Yan, Chen
    Newby, Andrew C.
    Rhaman, Arshad
    Berk, Bradford C.
    [J]. CIRCULATION RESEARCH, 2007, 101 (01) : 97 - 105
  • [19] Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-α signal transduction
    Gotoh, Y
    Cooper, JA
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (28) : 17477 - 17482
  • [20] Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69
    Haendeler, J
    Hoffmann, J
    Tischler, V
    Berk, BC
    Zeiher, AM
    Dimmeler, S
    [J]. NATURE CELL BIOLOGY, 2002, 4 (10) : 743 - 749