Biocompatibility of boron nitride nanosheets

被引：126

作者：

Mateti, Srikanth ^{[1
]}

Wong, Cynthia S. ^{[1
]}

Liu, Zhen ^{[2
]}

Yang, Wenrong ^{[2
]}

Li, Yuncang ^{[3
]}

Li, Lu Hua ^{[1
]}

Chen, Ying ^{[1
]}

机构：

[1] Deakin Univ, Inst Frontier Mat, Waurn Ponds, Vic 3216, Australia

[2] Deakin Univ, Sch Life & Environm Sci, Ctr Chem & Biotechnol, Waurn Ponds, Vic 3216, Australia

[3] RMIT Univ, Sch Engn, Melbourne, Vic 3001, Australia

来源：

NANO RESEARCH | 2018年 / 11卷 / 01期

基金：

澳大利亚研究理事会;

关键词：

boron nitride; nanosheet; biocompatibility; CARBON NANOTUBES; DRUG-DELIVERY; IN-VITRO; GRAPHENE; CELLS; SIZE; WS2; NANOPARTICLES; CYTOTOXICITY; COMPOSITES;

D O I：

10.1007/s12274-017-1635-y

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The properties and applications of boron nitride (BN) nanosheets are complementary to those of graphene, with advantages in chemical and thermal stability. Biocompatibility is an important property for future biomedical applications but has not been investigated experimentally. We studied the biocompatibility of BN nanosheets of different sizes and compared it with that of BN nanoparticles in osteoblast-like cells (SaOS(2)). Our results showed that the biocompatibility of BN nanomaterials depends on their size, shape, structure, and surface chemical properties. Electron spin resonance measurement revealed that unsaturated B atoms located at the nanosheet edges or on the particle surface are responsible for the cell death.

引用

页码：334 / 342

页数：9

共 39 条

[1] Functional Composite Materials Based on Chemically Converted Graphene [J].

Bai, Hua ;

Li, Chun ;

Shi, Gaoquan .

ADVANCED MATERIALS, 2011, 23 (09) :1089-1115

[2]

BRAND-WILLIAMS W, 1995, FOOD SCI TECHNOL-LEB, V28, P25

[3] CHARACTER AND ORIGIN OF VACUOLES INDUCED IN MAMMALIAN-CELLS BY THE CYTOTOXIN OF HELICOBACTER-PYLORI [J].

CATRENICH, CE ;

CHESTNUT, MH .

JOURNAL OF MEDICAL MICROBIOLOGY, 1992, 37 (06) :389-395

[4] Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells [J].

Chen, Y. ;

McMillan-Ward, E. ;

Kong, J. ;

Israels, S. J. ;

Gibson, S. B. .

CELL DEATH AND DIFFERENTIATION, 2008, 15 (01) :171-182

[5] Boron nitride nanotubes: Pronounced resistance to oxidation [J].

Chen, Y ;

Zou, J ;

Campbell, SJ ;

Le Caer, G .

APPLIED PHYSICS LETTERS, 2004, 84 (13) :2430-2432

[6] PEGylated WS2 Nanosheets as a Multifunctional Theranostic Agent for in vivo Dual-Modal CT/Photoacoustic Imaging Guided Photothermal Therapy [J].

Cheng, Liang ;

Liu, Jingjing ;

Gu, Xing ;

Gong, Hua ;

Shi, Xiaoze ;

Liu, Teng ;

Wang, Chao ;

Wang, Xiaoyong ;

Liu, Gang ;

Xing, Huaiyong ;

Bu, Wenbo ;

Sun, Baoquan ;

Liu, Zhuang .

ADVANCED MATERIALS, 2014, 26 (12) :1886-1893

[7] Cytocompatibility, Interactions, and Uptake of Polyethyleneimine-Coated Boron Nitride Nanotubes by Living Cells: Confirmation of Their Potential for Biomedical Applications [J].

Ciofani, Gianni ;

Raffa, Vittoria ;

Menciassi, Arianna ;

Cuschieri, Alfred .

BIOTECHNOLOGY AND BIOENGINEERING, 2008, 101 (04) :850-858

[8] Boron Nitride Nanotubes: A Novel Vector for Targeted Magnetic Drug Delivery [J].

Ciofani, Gianni ;

Raffa, Vittoria ;

Yu, Jun ;

Chen, Ying ;

Obata, Yosuke ;

Takeoka, Shinji ;

Menciassi, Arianna ;

Cuschieri, Alfred .

CURRENT NANOSCIENCE, 2009, 5 (01) :33-38

[9] Interaction of Boron Nitride Nanosheets with Model Cell Membranes [J].

Hilder, Tamsyn A. ;

Gaston, Nicola .

CHEMPHYSCHEM, 2016, 17 (11) :1573-1578

[10] In Vitro Investigation of the Cellular Toxicity of Boron Nitride Nanotubes [J].

Horvath, Lenke ;

Magrez, Arnaud ;

Golberg, Dmitri ;

Zhi, Chunyi ;

Bando, Yoshio ;

Smajda, Rita ;

Horvath, Endre ;

Forro, Laszlo ;

Schwaller, Beat .

ACS NANO, 2011, 5 (05) :3800-3810

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