Rare Presentation of Atypical Hemolytic Uremic Syndrome in an Adult

被引：0
作者：
Alhabhbeh, Ammar [1 ]
Fatima, Zainab [1 ]
Thomas, Akesh [2 ]
Cook, Christopher [2 ]
机构：
[1] East Tennessee State Univ, Internal Med, Johnson City, TN 37614 USA
[2] East Tennessee State Univ, Quillen Coll Med, Internal Med, Johnson City, TN USA
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2021年 / 13卷 / 09期
关键词：
eculizumab; acute renal failure; atypical hemolytic uremic syndrome (ahus); tma; thrombocytopenia; hemolytic anemia; microangiopathic hemolytic anemia; hus; COMPLEMENT INHIBITOR ECULIZUMAB; DIAGNOSIS;
D O I：
10.7759/cureus.18184
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Thrombotic microangiopathies (TMA) are disorders characterized by microangiopathic hemolytic anemia, thrombocytopenia, and microthrombi leading to organ dysfunction. Atypical hemolytic uremic syndrome (aHUS) is a rare subtype of TMA mediated by complement dysregulation. We present a case of a 59-year-old female who presented with acute kidney injury and mild thrombocytopenia but with normal hemoglobin. We highlight the importance of prompt diagnosis of aHUS and initiating appropriate treatment with eculizumab.
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