InCl3-Catalyzed Allylic Friedel-Crafts Reactions toward the Stereocontrolled Synthesis of 1,2,3,4-Tetrahydroquinolines

被引：19

作者：

Giera, David S. ^{[1
]}

Schneider, Christoph ^{[1
]}

机构：

[1] Univ Leipzig, Inst Organ Chem, D-04103 Leipzig, Germany

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 21期

关键词：

IRIDIUM-CATALYZED HYDROGENATION; REISSERT-TYPE REACTION; RECENT PROGRESS; ACID; EFFICIENT; TETRAHYDROQUINOLINES; HETEROCYCLES; DERIVATIVES; QUINOLINES; ROUTE;

D O I：

10.1021/ol102023z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Allyl chlorides tethered to an N-aryl moiety readily undergo InCl3-catalyzed Friedel Crafts reactions to furnish highly enantiomerically enriched 1,2,3,4-tetrahydroquinolines with good yields and excellent diastereoselectivity.

引用

页码：4884 / 4887

页数：4

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