True Unilateral Mandibular Cherubism: A Literature Review and Case Report

被引：1

作者：

Johnston, Darin T. ^{[1
]}

Hudson, John W. ^{[1
]}

Wells, Nathaniel G. ^{[1
]}

Pickup, Jason D. ^{[1
]}

机构：

[1] Univ Tennessee, Med Ctr, Dept Oral & Maxillofacial Surg, 1930 Alcoa Hwy, Knoxville, TN 37920 USA

来源：

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 2020年 / 78卷 / 02期

关键词：

GIANT-CELL GRANULOMA; GENE; THERAPY;

D O I：

10.1016/j.joms.2019.08.027

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Cherubism is a self-limiting fibro-osseous disorder that is classically characterized by bilateral mandibular swelling in the first or second decade of life. Three cases of unilateral cherubism have been described in the literature; however, bilateral involvement did not eventually develop in only 1 case. Histopathologic variation and genetic heterogeneity complicate the diagnosis and treatment of a unilateral benign giant cell lesion of the jaws. Our case report presents a 13-year-old male patient with unilateral posterior mandibular swelling that proved to be histologically and clinically consistent with unilateral cherubism. Involution of the unilateral lesion with no bilateral involvement occurred during 8 years of serial examination. (C) 2019 American Association of Oral and Maxillofacial Surgeons

引用

页码：228 / 234

页数：7

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