A volumetric magnetic resonance imaging study of monozygotic twins discordant for bipolar disorder

被引：112
作者：
Noga, JT
Vladar, K
Torrey, EF
机构：
[1] Emory Univ, Dept Psychiat, Atlanta, GA 30322 USA
[2] Univ Maryland, Dept Psychiat, Baltimore, MD 21201 USA
[3] Stanley Res Fdn, Bethesda, MD USA
来源：
PSYCHIATRY RESEARCH-NEUROIMAGING | 2001年 / 106卷 / 01期
关键词：
bipolar disorder; MRI; hippocampus; striatum;
D O I：
10.1016/S0925-4927(00)00084-6
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Six monozygotic (MZ) twin pairs discordant for bipolar disorder were compared with normal MZ twins with magnetic resonance imaging (MRI) on volumes of basal ganglia (BC), amygdala-hippocampus (AH), and cerebral hemisphere. Caudate nuclei were larger in both affected and unaffected bipolar twins than in normal MZ twins. The right hippocampus was smaller in the sick vs. well bipolar twins. The hippocampus was also less asymmetric in the affected bipolar twins than in the well cotwins and the normal MZ twins. These anatomical structures continue to be of interest in bipolar disorder research. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码：25 / 34
页数：10
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