Trends in the development of nucleic acid biosensors for medical diagnostics

被引：52

作者：

Piunno, PAE ^{[1
]}

Krull, UJ ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem & Phys Sci, Chem Sensors Grp, Mississauga, ON L5L 1C6, Canada

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2005年 / 381卷 / 05期

关键词：

biosensors; nucleic acids; hybridization; amplification; sensitivity; selectivity;

D O I：

10.1007/s00216-004-3024-0

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Some of the recent advances in the field of biosensors for nucleic acid analysis in medical diagnostic applications are highlighted. Particular attention is paid in this review to the progress made in two key areas of development: (i) enhancements achieved in device selectivity, and (ii) enhancements achieved in device sensitivity.

引用

页码：1004 / 1011

页数：8

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