Role of sorafenib in renal cell carcinoma: focus on elderly patients

被引：0

作者：

Procopio, Giuseppe ^{[1
]}

机构：

[1] Fdn Ist Nazl Tumori, I-20133 Milan, Italy

来源：

EXPERT REVIEW OF ANTICANCER THERAPY | 2011年 / 11卷 / 11期

关键词：

elderly; renal cell cancer; sorafenib; targeted therapies; EXPANDED-ACCESS; OLDER PATIENTS; EFFICACY; SAFETY;

D O I：

10.1586/ERA.11.153

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mounting evidence suggests that, in order to optimize therapeutic benefits, it is important to consider the range of parameters and characteristics relevant to each individual patient. Of note, the six targeted therapies currently approved for the treatment of advanced/metastatic renal cell carcinoma have not been evaluated in all relevant settings and in all prognostic groups. Among different agents currently licensed for the treatment of renal cell carcinoma, sorafenib was the first therapy to show improvements in progression-free survival and overal survival in Phase III trials. This article will discuss the current role of sorafenib in the treatment of elderly patients with renal cell carcinoma.

引用

页码：1689 / 1692

页数：4

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