Treatment of Hepatitis C Virus Infection in Kidney Transplant Recipients: Case Report

被引：7

作者：

Caeiro, F. ^{[1
]}

Baptista, V. ^{[1
]}

Rodrigues, N. ^{[1
]}

Carvalho, D. ^{[1
]}

Aires, I. ^{[1
]}

Remedio, F. ^{[1
]}

Nolasco, F. ^{[1
]}

机构：

[1] Hosp Curry Cabral, Dept Nephrol, Lisbon, Portugal

来源：

TRANSPLANTATION PROCEEDINGS | 2011年 / 43卷 / 01期

关键词：

FIBROSING CHOLESTATIC HEPATITIS; RENAL-TRANSPLANTATION; SURVIVAL; THERAPY; DISEASE;

D O I：

10.1016/j.transproceed.2011.01.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Chronic hepatitis C virus (HCV) infection exists in a large proportion of patients undergoing renal transplantation. Nowadays it is not considered to be an absolute contraindication to transplantation; however, it is associated with an increased risk for the patient and accounts for a shorter half-life of the renal allograft. We present three transplant recipients who displayed serious hepatic dysfunction after renal transplantation due to an HCV infection. In two of these cases, the liver biopsies established the diagnosis of FCH. In the third case, the liver biopsy was compatible with the early stages of FCH. All patients were started on peg-interferon alfa 2-b and ribavirin with subsequent normalization of hepatic function and early complete viral responses.

引用

页码：259 / 262

页数：4

共 11 条

[1]

Batty DS, 2001, AM J TRANSPLANT, V1, P179, DOI 10.1034/j.1600-6143.2001.10213.x

[2]

BUSTILLO ED, 1998, J AM SOC NEPHROL, V9, P1109

[3] HEPATIC HISTOLOGICAL-FINDINGS AFTER TRANSPLANTATION FOR CHRONIC HEPATITIS-B VIRUS-INFECTION, INCLUDING A UNIQUE PATTERN OF FIBROSING CHOLESTATIC HEPATITIS [J].