Variability in Practices of Compounding Budesonide for Eosinophilic Esophagitis

被引:10
作者
Joshi, Sagar [1 ]
Rubenstein, Joel H. [2 ,3 ]
Dellon, Evan S. [4 ]
Worthing, Nathan [5 ]
Stefanadis, Zoe [6 ]
Chang, Joy W. [3 ]
机构
[1] Univ Michigan, Dept Internal Med, Ann Arbor, MI 48109 USA
[2] Ann Arbor VA Med Ctr, Vet Affairs Ctr Clin Management Res, Ann Arbor, MI USA
[3] Univ Michigan, Dept Internal Med, Div Gastroenterol, Ann Arbor, MI 48109 USA
[4] Univ N Carolina, Ctr Esophageal & Swallowing Disorders, Div Gastroenterol, Chapel Hill, NC 27515 USA
[5] Clark Profess Pharm, Ann Arbor, MI USA
[6] Chapel Hill Compounding Pharm, Chapel Hill, NC USA
关键词
MANAGEMENT;
D O I
10.14309/ajg.0000000000001170
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
INTRODUCTION: Little is known about the use of compounded steroids for eosinophilic esophagitis (EoE). METHODS: We conducted a telephone survey of all compounding pharmacies in Michigan and queried about practices and costs of compounded budesonide for EoE. RESULTS: Of 68 Michigan pharmacies, 93% responded, and 20 (29%) offer compounded budesonide suspension for EoE. Formulations, dose, and instructions for use varied across pharmacies. The mean cost for a 30-day supply was $74.50. DISCUSSION: Although few compounding pharmacies offer budesonide suspension and there are substantial variations in formulations, this may be a significantly more affordable treatment option for many.
引用
收藏
页码:1336 / 1338
页数:3
相关论文
共 12 条
[1]  
Alexander Jeffrey A, 2014, Gastroenterol Hepatol (N Y), V10, P327
[2]   Mucoadhesive Budesonide Formulation for the Treatment of Eosinophilic Esophagitis [J].
Casiraghi, Antonella ;
Gennari, Chiara Grazia ;
Musazzi, Umberto Maria ;
Ortenzi, Marco Aldo ;
Bordignon, Susanna ;
Minghetti, Paola .
PHARMACEUTICS, 2020, 12 (03)
[3]   Cost Utility Analysis of Topical Steroids Compared With Dietary Elimination for Treatment of Eosinophilic Esophagitis [J].
Cotton, Cary C. ;
Erim, Daniel ;
Eluri, Swathi ;
Palmer, Sarah H. ;
Green, Daniel J. ;
Wolf, W. Asher ;
Runge, Thomas M. ;
Wheeler, Stephanie ;
Shaheen, Nicholas J. ;
Dellon, Evan S. .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2017, 15 (06) :841-+
[4]   Cost-effective care in eosinophilic esophagitis [J].
Dellon, Evan S. .
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2019, 123 (02) :166-172
[5]   ACG Clinical Guideline: Evidenced Based Approach to the Diagnosis and Management of Esophageal Eosinophilia and Eosinophilic Esophagitis (EoE) [J].
Dellon, Evan S. ;
Gonsalves, Nirmala ;
Hirano, Ikuo ;
Furuta, Glenn T. ;
Liacouras, Chris A. ;
Katzka, David A. .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2013, 108 (05) :679-692
[6]   A Randomized Controlled Comparison of Esophageal Clearance Times of Oral Budesonide Preparations [J].
Hefner, Jody N. ;
Howard, Robin S. ;
Massey, Robert ;
Valencia, Miland ;
Stocker, Derek J. ;
Philla, Katherine Q. ;
Goldman, Matthew D. ;
Nylund, Cade M. ;
Min, Steve B. .
DIGESTIVE DISEASES AND SCIENCES, 2016, 61 (06) :1582-1590
[7]   AGA Institute and the Joint Task Force on Allergy-Immunology Practice Parameters Clinical Guidelines for the Management of Eosinophilic Esophagitis [J].
Hirano, Ikuo ;
Chan, Edmond S. ;
Rank, Matthew A. ;
Sharaf, Rajiv N. ;
Stollman, Neil H. ;
Stukus, David R. ;
Wang, Kenneth ;
Greenhawt, Matthew ;
Falck-Ytter, Yngve T. .
GASTROENTEROLOGY, 2020, 158 (06) :1776-1786
[8]   Treatment with compounded fluticasone suspension improves the clinical, endoscopic, and histologic features of eosinophilic esophagitis [J].
Ketchem, Corey J. ;
Reed, Craig C. ;
Stefanadis, Zoe ;
Dellon, Evan S. .
DISEASES OF THE ESOPHAGUS, 2021, 34 (07)
[9]   Oral viscous budesonide can be successfully delivered through a variety of vehicles to treat eosinophilic esophagitis in children [J].
Lee, Juhee ;
Shuker, Michelle ;
Brown-Whitehorn, Terri ;
Cianferoni, Antonella ;
Gober, Laura ;
Muir, Amanda ;
Verma, Ritu ;
Liacouras, Chris ;
Spergel, Jonathan M. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2016, 4 (04) :767-768
[10]   Health-Related Quality of Life and Costs Associated With Eosinophilic Esophagitis: A Systematic Review [J].
Mukkada, Vincent ;
Falk, Gary W. ;
Eichinger, Christian S. ;
King, Denise ;
Todorova, Lora ;
Shaheen, Nicholas J. .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2018, 16 (04) :495-+