Spontaneous T wave alternans in a patient with Brugada syndrome - Responses to intravenous administration of class I antiarrhythmic drug, glucose tolerance test, and atrial pacing

被引:32
作者
Nishizaki, M
Fujii, H
Sakurada, H
Kimura, A
Hiraoka, M
机构
[1] Yokohama Minami Kyosai Hosp, Dept Cardiol, Yokohama, Kanagawa 2360037, Japan
[2] Tokyo Metropolitan Hiroo Gen Hosp, Dept Cardiol, Tokyo, Japan
[3] Tokyo Med & Dent Univ, Med Res Inst, Dept Mol Pathogenesis, Tokyo, Japan
[4] Tokyo Med & Dent Univ, Med Res Inst, Dept Cardiovasc Dis, Tokyo, Japan
关键词
Brugada syndrome; T wave alternans; class I antiarrhythmic drug; glucose tolerance test; atrial pacing; insulin;
D O I
10.1046/j.1540-8167.2004.40411.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Spontaneous T Wave Alternans in Brugada Syndrome. A 43-year-old man with an episode of syncope showed ECG patterns of coved-type ST elevation in leads V1-V3 and right bundle branch block pattern. The patient had spontaneous T wave alternans at baseline, and T wave alternans diminished with distinct development of ST elevation after administration of Na+ channel blocker, and during oral glucose load and atrial pacing. Na+ channel mutation may contribute to the genesis of his ECG changes.
引用
收藏
页码:217 / 220
页数:4
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