Lipophilicity determination of some 1-1, 2, 4-triazole compounds by reversed-phase thin layer chromatography

被引：0

作者：

Jiang, JZ ^{[1
]}

Zhang, ZC ^{[1
]}

Yin, BL ^{[1
]}

Zhao, GF ^{[1
]}

Wang, QS ^{[1
]}

机构：

[1] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE | 2001年 / 22卷 / 05期

关键词：

RP-HPTLC; 1-1; 2; 4-triazole compounds quantitative relationship between structure and retention value; hydrophobic parameter;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A study has been carried out of evaluating lipophilicity of some 1-1 2, 4-triazole compounds by RP-HPTLC. An equation that reasonably correlates partition coefficients(clgP) with R-M0 values for 23 1-1,2,4-triazole compounds was derived and its predictive capability was tested with five 1-1,2,4-triazole compounds. It has been found that RP-HPTLC can be extensively applied to determining lipophilicity of 1-1,2,4-triazole compounds.

引用

页码：788 / 790

页数：3

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