A feasibility study of a rotary planar electrode array for electrical impedance mammography using a digital breast phantom

被引:8
作者
Zhang, X. [1 ]
Chatwin, C. [1 ]
Barber, D. C. [2 ]
机构
[1] Univ Sussex, Dept Engn, Brighton BN1 9QT, E Sussex, England
[2] Univ Sheffield, Dept Cardiovasc Sci, Sheffield S1 4DT, S Yorkshire, England
关键词
breast cancer detection; breast phantom; electrical impedance mammography; electrical impedance tomography; DIELECTRIC-PROPERTIES; IMAGE-RECONSTRUCTION; L-CURVE; TOMOGRAPHY; TISSUE; EIT; REGULARIZATION; IMPEDIVITY;
D O I
10.1088/0967-3334/36/6/1311
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A feasibility study of an electrical impedance mammography (EIM) system with a rotary planar electrode array, named RPEIM, is presented. The RPEIM system is an evolution of the Sussex MK4 system, which is a prototype instrument for breast cancer detection. Comparing it with the other planar electrode EIM systems, the rotation feature enables a dramatic increase in the number of independent measurements. To assist impedance evaluation exploiting electrode array rotation, a synchronous mesh method is proposed. Using the synchronous mesh method, the RPEIM system is shown to have superior performance in image accuracy, spatial resolution and noise tolerance over the MK4 system. To validate the study, we report simulations based on a close-to-realistic 3D digital breast phantom, which comprises of: skin, nipple, ducts, acinus, fat and tumor. A digital breast phantom of a real patient is constructed, whose tumor was detected using the MK4 system. The reconstructed conductivity image of the breast phantom indicates that the breast phantom is a close replica of the patient's real breast as assessed by the MK4 system in a clinical trial. A comparison between the RPEIM system and the MK4 system is made based on this phantom to assess the advantages of the RPEIM system.
引用
收藏
页码:1311 / 1335
页数:25
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