Biomedical Applications of Glycoconjugates

被引：6

作者：

Ding, Fei ^{[1
]}

Zhang, Yongmin ^{[1
,2
]}

机构：

[1] Jianghan Univ, Inst Interdisciplinary Res, Wuhan Econ & Technol Dev Zone, Wuhan 430056, Hubei, Peoples R China

[2] Univ Pierre & Marie Curie Paris 6, CNRS UMR 8232, Inst Parisien Chim Mol, 4 Pl Jussieu, F-75005 Paris, France

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2018年 / 18卷 / 18期

基金：

中国国家自然科学基金;

关键词：

Drug delivery; glycoconjugates; glycolipid; glycopeptide; glycoprotein; targeting; TARGETED DRUG-DELIVERY; IN-VITRO; TRANSFERRIN; DOXORUBICIN; CARRIERS; NANOPARTICLES; CONJUGATE; MICELLES; THERAPY; RELEASE;

D O I：

10.2174/1389557518666180518083427

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Glycans expressed on the forefront surface of cells participate in many key biological processes via forming various glycoconjugates. The recognition of complex glycoconjugates as mediators of important biological processes has stimulated investigation into their therapeutic potential. As the increasing accessibility of glycoconjugates, it has been widely applied in the field of drug delivery. This review particularly refers to the constitutive glycoconjugates of receptor-mediated binding of glycoprotein, glycolipids and glycopeptides for cell-selective drug delivery, in order to broaden the future therapeutic scope of drug delivery system and effective cancer therapy.

引用

页码：1508 / 1523

页数：16

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