Pemphigus vulgaris induced by 5-aminolaevulinic acid-based photodynamic therapy

被引：12

作者：

Zhou, Qian ^{[1
]}

Wang, Peiru ^{[1
]}

Zhang, Linglin ^{[1
]}

Wang, Bo ^{[1
]}

Shi, Lei ^{[1
]}

Keyal, Uma ^{[1
]}

Bhatta, Anil Kumar ^{[1
]}

Zhang, Guolong ^{[1
]}

Wang, Xiuli ^{[1
]}

机构：

[1] Tongji Univ, Inst Photomed, Shanghai Skin Dis Hosp, Sch Med, 1278 Baode Rd, Shanghai 200443, Peoples R China

来源：

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY | 2017年 / 19卷

基金：

上海市自然科学基金; 中国国家自然科学基金;

关键词：

Photodynamic therapy; Pemphigus vulgaris; Basal cell carcinoma; Reactive oxygen species;

D O I：

10.1016/j.pdpdt.2017.05.014

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Pemphigus vulgaris (PV) is an autoimmune disorder resulting from the interaction between autoantibodies and desmoglein. Here, we report a case of PV developed after 5-aminolaevulinic acid-based photodynamic therapy (ALA-PDT). The harmful and deleterious effects of UV radiation on the onset, during course, and perpetuation of PV have been observed for decades. Correlation between reactive oxygen species (ROS) and PV have also been reported. Oxidative proteins, which are modified by ROS, and subsequent production of antibodies by immune system seem to be responsible for PV developed following ALA-PDT. We emphasize that ALA-PDT should be added to the list of possible factors triggering PV and this condition should be considered if blistering arises following ALA-PDT.

引用

页码：156 / 158

页数：3

共 6 条

[1] Catalase and Lipid Peroxidation Values in Serum of Tunisian Patients with Pemphigus Vulgaris and Foliaceus [J].