How I treat juvenile idiopathic arthritis: A state of the art review

被引:27
作者
Cimaz, Rolando [1 ,2 ]
Marino, Achille [1 ,2 ]
Martini, Alberto [3 ,4 ]
机构
[1] Azienda Oospedaliera Univ Anna Meyer, Florence, Italy
[2] Univ Firenze, Florence, Italy
[3] Ist Giannina Gaslini, Genoa, Italy
[4] Univ Genoa, Genoa, Italy
关键词
MACROPHAGE ACTIVATION SYNDROME; ENTHESITIS-RELATED ARTHRITIS; PLACEBO-CONTROLLED TRIAL; LONG-TERM SAFETY; INTRAARTICULAR CORTICOSTEROID INJECTIONS; INTERLEUKIN-1 RECEPTOR ANTAGONIST; INFLIXIMAB PLUS METHOTREXATE; DOUBLE-BLIND; OPEN-LABEL; RHEUMATOID-ARTHRITIS;
D O I
10.1016/j.autrev.2017.07.014
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children and an important cause of short and long-term disability. JIA encompasses several disease categories, each of which has distinct presentation, clinical manifestations, and, presumably, genetic background and etiopathogenesis. Correct choice and timely use of available medications to achieve early and sustained remission with as few side effects as possible remain challenges for the treating physician. This review aims to provide daily practical advice for the treatment of JIA patients on the basis of both our experience and existing recommendations. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:1008 / 1015
页数:8
相关论文
共 122 条
[21]  
Consolaro A, 2014, CLIN EXP RHEUMATOL, V32, pS126
[22]   Development and Validation of a Composite Disease Activity Score for Juvenile Idiopathic Arthritis [J].
Consolaro, Alessandro ;
Ruperto, Nicolino ;
Bazso, Anna ;
Pistorio, Angela ;
Magni-Manzoni, Silvia ;
Filocamo, Giovanni ;
Malattia, Clara ;
Viola, Stefania ;
Martini, Alberto ;
Ravelli, Angelo .
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH, 2009, 61 (05) :658-666
[23]   The mechanism of action of methotrexate [J].
Cronstein, BN .
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 1997, 23 (04) :739-+
[24]   Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF-TNF-RII binding in rheumatoid arthritis [J].
Dao Xuan Nguyen ;
Ehrenstein, Michael R. .
JOURNAL OF EXPERIMENTAL MEDICINE, 2016, 213 (07) :1241-1253
[25]  
De Benedetti F, 1998, J RHEUMATOL, V25, P203
[26]   Randomized Trial of Tocilizumab in Systemic Juvenile Idiopathic Arthritis [J].
De Benedetti, Fabrizio ;
Brunner, Hermine I. ;
Ruperto, Nicolino ;
Kenwright, Andrew ;
Wright, Stephen ;
Calvo, Inmaculada ;
Cuttica, Ruben ;
Ravelli, Angelo ;
Schneider, Rayfel ;
Woo, Patricia ;
Wouters, Carine ;
Xavier, Ricardo ;
Zemel, Lawrence ;
Baildam, Eileen ;
Burgos-Vargas, Ruben ;
Dolezalova, Pavla ;
Garay, Stella M. ;
Merino, Rosa ;
Joos, Rik ;
Grom, Alexei ;
Wulffraat, Nico ;
Zuber, Zbigniew ;
Zulian, Francesco ;
Lovell, Daniel ;
Martini, Alberto .
NEW ENGLAND JOURNAL OF MEDICINE, 2012, 367 (25) :2385-2395
[27]   Methotrexate Withdrawal at 6 vs 12 Months in Juvenile Idiopathic Arthritis in Remission A Randomized Clinical Trial [J].
Foell, Dirk ;
Wulffraat, Nico ;
Wedderburn, Lucy R. ;
Wittkowski, Helmut ;
Frosch, Michael ;
Gerss, Joachim ;
Stanevicha, Valda ;
Mihaylova, Dimitrina ;
Ferriani, Virginia ;
Tsakalidou, Florence Kanakoudi ;
Foeldvari, Ivan ;
Cuttica, Ruben ;
Gonzalez, Benito ;
Ravelli, Angelo ;
Khubchandani, Raju ;
Oliveira, Sheila ;
Armbrust, Wineke ;
Garay, Stella ;
Vojinovic, Jelena ;
Norambuena, Ximena ;
Gamir, Maria Luz ;
Garcia-Consuegra, Julia ;
Lepore, Loredana ;
Susic, Gordana ;
Corona, Fabrizia ;
Dolezalova, Pavla ;
Pistorio, Angela ;
Martini, Alberto ;
Ruperto, Nicolino ;
Roth, Johannes .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 303 (13) :1266-1273
[28]  
Frosch M, 2000, ARTHRITIS RHEUM-US, V43, P628, DOI 10.1002/1529-0131(200003)43:3<628::AID-ANR20>3.0.CO
[29]  
2-X
[30]   The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis [J].
Gattorno, Marco ;
Piccini, Alessandra ;
Lasiglie, Denise ;
Tassi, Sara ;
Brisca, Giacomo ;
Carta, Sonia ;
Delfino, Laura ;
Ferlito, Francesca ;
Pelagatti, Maria Antonietta ;
Caroli, Francesco ;
Buoncompagni, Antonella ;
Viola, Stefania ;
Loy, Anna ;
Sironi, Marina ;
Vecchi, Annunciata ;
Ravelli, Angelo ;
Martini, Alberto ;
Rubartelli, Anna .
ARTHRITIS AND RHEUMATISM, 2008, 58 (05) :1505-1515