How I treat juvenile idiopathic arthritis: A state of the art review

被引:27
作者
Cimaz, Rolando [1 ,2 ]
Marino, Achille [1 ,2 ]
Martini, Alberto [3 ,4 ]
机构
[1] Azienda Oospedaliera Univ Anna Meyer, Florence, Italy
[2] Univ Firenze, Florence, Italy
[3] Ist Giannina Gaslini, Genoa, Italy
[4] Univ Genoa, Genoa, Italy
关键词
MACROPHAGE ACTIVATION SYNDROME; ENTHESITIS-RELATED ARTHRITIS; PLACEBO-CONTROLLED TRIAL; LONG-TERM SAFETY; INTRAARTICULAR CORTICOSTEROID INJECTIONS; INTERLEUKIN-1 RECEPTOR ANTAGONIST; INFLIXIMAB PLUS METHOTREXATE; DOUBLE-BLIND; OPEN-LABEL; RHEUMATOID-ARTHRITIS;
D O I
10.1016/j.autrev.2017.07.014
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children and an important cause of short and long-term disability. JIA encompasses several disease categories, each of which has distinct presentation, clinical manifestations, and, presumably, genetic background and etiopathogenesis. Correct choice and timely use of available medications to achieve early and sustained remission with as few side effects as possible remain challenges for the treating physician. This review aims to provide daily practical advice for the treatment of JIA patients on the basis of both our experience and existing recommendations. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:1008 / 1015
页数:8
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