Cucurbitane-Type Triterpenoids from Momordica charantia

被引：47
作者：
Ma, Jun [1 ]
Whittaker, Paul [1 ]
Keller, Amy C. [2 ,3 ]
Mazzola, Eugene P. [1 ]
Pawar, Rahul S. [1 ]
White, Kevin D. [1 ]
Callahan, John H. [1 ]
Kennelly, Edward J. [2 ,3 ]
Krynitsky, Alexander J. [1 ]
Rader, Jeanne I. [1 ]
机构：
[1] US FDA, Off Regulatory Sci, Ctr Food Safety & Appl Nutr, College Pk, MD 20740 USA
[2] CUNY Herbert H Lehman Coll, Dept Biol Sci, Bronx, NY 10468 USA
[3] CUNY, Grad Ctr, Bronx, NY USA
来源：
PLANTA MEDICA | 2010年 / 76卷 / 15期
关键词：
Momordica charantia; Cucurbitaceae; cucurbitane-type triterpenoid; momordicoside U; OVIPOSITION DETERRENT; LIRIOMYZA-TRIFOLII; GLYCOSIDES; CONSTITUENTS; LEAFMINER; LEAVES; FRUITS;
D O I：
10.1055/s-0030-1249807
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
One new cucurbitane-type triterpenoid glycoside, momordicoside U (1), together with five known cucurbitane-type triterpenoids and related glycosides, 3 beta,7 beta,25-trihydroxycucurbita-5,23 (E)-dien-19-al (2), momordicine I(3), momordicine II(4), 3-hydroxycucurbita-5,24-dien-19-al-7,23-di-O-beta-glucopyranoside (5), and kuguaglycoside G (6), were isolated from the whole plant of Momordica charantia. Their structures were determined by chemical and spectroscopic methods. Momordicoside U (1) was evaluated for insulin secretion activity in an in vitro insulin secretion assay and displayed moderate activity.
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收藏
页码：1758 / 1761
页数：4
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