Deep brain stimulation of the orbitofrontal projections for the treatment of intermittent explosive disorder

被引：21

作者：

Maley, Jason H. ^{[1
]}

Alvernia, Jorge E. ^{[1
]}

Valle, Edison P. ^{[1
]}

Richardson, Donald ^{[1
]}

机构：

[1] Tulane Univ, Sch Med, Dept Neurosurg, New Orleans, LA 70112 USA

来源：

NEUROSURGICAL FOCUS | 2010年 / 29卷 / 02期

关键词：

deep brain stimulation; orbitofrontal cortex; intermittent explosive disorder; POSITRON-EMISSION; AGGRESSION; BEHAVIOR; AMYGDALOTOMY; EMOTION; CORTEX;

D O I：

10.3171/2010.5.FOCUS10102

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Intermittent explosive disorder (IED) is characterized by a dysfunction in the greater limbic system leading an individual to experience sudden aggressive behavior with little or no environmental perturbation. This report describes a procedure for the treatment of IED in a 19-year-old woman with a history of IED, having had episodes of severe violent attacks against family, dating to early childhood. Due to the severity and intractability of the illness, deep brain stimulation was performed, targeting the orbitofrontal projections to the hypothalamus. The patient's history and the procedure, management, and rationale are described in detail. (DOI: 10.3171/2010.5.FOCUS10102)

引用

页码：1 / 5

页数：5

共 28 条

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