Similarities of Variant Creutzfeldt-Jakob Disease Strain in Mother and Son in Spain to UK Reference Case

被引：5

作者：

Diack, Abigail B. ^{[1
]}

Boyle, Aileen ^{[1
]}

Ritchie, Diane ^{[2
]}

Plinston, Chris ^{[1
]}

Kisielewski, Dorothy ^{[1
]}

de Pedro-Cuesta, Jesus ^{[3
]}

Rabano, Alberto ^{[3
]}

Will, Robert G. ^{[2
]}

Manson, Jean C. ^{[1
]}

机构：

[1] Roslin Inst, Easter Bush, Scotland

[2] Univ Edinburgh, Edinburgh, Midlothian, Scotland

[3] Carlos III Inst Hlth, Madrid, Spain

来源：

EMERGING INFECTIOUS DISEASES | 2017年 / 23卷 / 09期

基金：

英国医学研究理事会; 英国生物技术与生命科学研究理事会;

关键词：

SCRAPIE; MICE;

D O I：

10.3201/eid2309.170159

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We investigated transmission characteristics of variant Creutzfeldt-Jakob disease in a mother and son from Spain. Despite differences in patient age and disease manifestations, we found the same strain properties in these patients as in UK vCJD cases. A single strain of agent appears to be responsible for all vCJD cases to date.

引用

页码：1593 / 1596

页数：4

共 8 条

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