Inhibition of biochemical reactions by silicon nanowires through modulating enzyme activities

被引：8
|
作者：
Yi, Changqing
Fong, Chi-Chun
Chen, Weiwei
Qi, Suijian
Lee, Shuit-Tong [1 ]
Yang, Mengsu
机构：
[1] City Univ Hong Kong, Ctr Super Diamond & Adv Films, Hong Kong, Hong Kong, Peoples R China
[2] City Univ Hong Kong, Dept Phys & Mat Sci, Hong Kong, Hong Kong, Peoples R China
[3] City Univ Hong Kong, Dept Biol & Chem, Hong Kong, Hong Kong, Peoples R China
来源：
CHEMBIOCHEM | 2007年 / 8卷 / 11期
关键词：
D O I：
10.1002/cbic.200700136
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
(Figure Presented) Through the wire. We have investigated the potential effects of silicon nanowires (SiNW-SiO2) and SiNWs functionalized with carboxylic groups (SiNW-COOH) on restriction endonucleases and Taq DNA polymerase. The results show that these SiNWs can inhibit enzyme activity (lower band in gel). Our findings suggest that this could be due to chemical interactions between the functional groups on SiNWs and the enzymes. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：1225 / 1229
页数：5
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