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AtsPLA2-α nuclear relocalization by the Arabidopsis transcription factor AtMYB30 leads to repression of the plant defense response
被引:77
作者:
Froidure, Solene
[1
]
Canonne, Joanne
[1
]
Daniel, Xavier
[1
]
Jauneau, Alain
[2
]
Briere, Christian
[3
]
Roby, Dominique
[1
]
Rivas, Susana
[1
]
机构:
[1] Ctr Natl Rech Sci, Unite Mixte Rech, LIPM, Inst Natl Rech Agronom 2594 441, F-31320 Castanet Tolosan, France
[2] Inst Federatif Rech 40, Pole Biotechnol Vegetale, F-31320 Castanet Tolosan, France
[3] Univ Toulouse 3, Ctr Natl Rech Sci, Univ Toulouse Unite Mixte Rech, F-31326 Castanet Tolosan, France
来源:
关键词:
hypersensitive response;
MYB transcription factor;
secretory phospholipase;
plant disease resistance;
HYPERSENSITIVE CELL-DEATH;
CYTOSOLIC PHOSPHOLIPASE A(2);
CYSTEINE PROTEASE;
INNATE IMMUNITY;
R2R3-MYB GENE;
ACTIVATION;
THALIANA;
ACID;
IDENTIFICATION;
RESISTANCE;
D O I:
10.1073/pnas.1009056107
中图分类号:
O [数理科学和化学];
P [天文学、地球科学];
Q [生物科学];
N [自然科学总论];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
The hypersensitive response (HR), characterized by a rapid and localized cell death at the inoculation site, is one of the most efficient resistance reactions to pathogen attack in plants. The transcription factor AtMYB30 was identified as a positive regulator of the HR and resistance responses during interactions between Arabidopsis and bacteria. Here, we show that AtMYB30 and the secreted phospholipase AtsPLA(2)-alpha physically interact in vivo, following the AtMYB30-mediated specific relocalization of AtsPLA(2)-alpha from cytoplasmic vesicles to the plant cell nucleus. This protein interaction leads to repression of AtMYB30 transcriptional activity and negative regulation of plant HR. Moreover, Atspla(2)-alpha mutant plants are more resistant to bacterial inoculation, whereas AtsPLA(2)-alpha overexpression leads to decreased resistance, confirming that AtsPLA(2)-alpha is a negative regulator of AtMYB30-mediated defense. These data underline the importance of cellular dynamics and, particularly, protein translocation to the nucleus, for defense-associated gene regulation in plants.
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页码:15281 / 15286
页数:6
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