rac-Ethyl 4-hydroxy-6-(2-hydroxyphenyl)-2-oxo-4-(trifluoromethyl)perhydropyrimidine-5-carboxylate

被引:0
|
作者
Song, Xiao-Ping [1 ]
Li, Gong-Chun [1 ]
Zhu, Feng-Xiang [1 ]
Wu, Chang-Zeng [1 ]
机构
[1] Xuchang Univ, Coll Chem & Chem Engn, Xuchang 461000, Henan Province, Peoples R China
关键词
MITOTIC KINESIN EG5;
D O I
10.1107/S1600536810021355
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
In the title compound, C(14)H(15)F(3)N(2)O(5), prepared by reaction of 2-hydroxybenzaldehyde, ethyl 4,4,4-trifluoro-3-oxobutanoate and urea, the tetrapyrimidine ring adopts a half-chair conformation. The crystal structure is stabilized by five intermolecular hydrogen bonds, three O-H center dot center dot center dot O and two N-H center dot center dot center dot O, giving cyclic dimers (through three hydrogen bonds) which are further extended into a two-dimensional network.
引用
收藏
页码:O1651 / U111
页数:10
相关论文
共 50 条
  • [1] Ethyl 4-hydroxy-6-(4-hydroxyphenyl)-4-trifluoromethyl-2-sulfanylidene-1,3-diazinane-5-carboxylate ethanol monosolvate
    Yang, Feng-Ling
    Fa, Wen-Jun
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O1280 - U1811
  • [2] Ethyl 4-(2-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
    Qing-Fang, Cheng
    Xu, Xing-You
    Bao, Jing-Yan
    Zhang, Chun-Fang
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O2391 - O2392
  • [3] Ethyl 6-ethoxycarbonylmethyl-4-(2-hydroxyphenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
    Kettmann, Viktor
    Svetlik, Jan
    Veizerova, Lucia
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1092 - U2311
  • [4] rac-Ethyl 6-hydroxy-6-methyl-3-oxo-4-phenyl-1,3,4,5,6,7-hexahydrobenzo[c][1,2]oxazole-5-carboxylate
    Ismiyev, Arif I.
    Maharramov, Abel M.
    Rashidov, Bahruz A.
    Mammadova, Gunay Z.
    Askerov, Rizvan K.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O3018 - U1249
  • [5] Synthesis, structural, spectroscopical and DFT studies on third order NLO crystal: Ethyl-5-hydroxy-4-(2-hydroxyphenyl)-2-oxo-6-(trifluoromethyl) hexahydropyrimidine5-carboxylate (EHOTHPC)
    Sathiya, S.
    Senthilkumar, M.
    Umarani, P.
    JOURNAL OF MOLECULAR STRUCTURE, 2021, 1224
  • [6] Ethyl 6-[4-(dimethylamino)phenyl]-4-hydroxy-2-oxo-4-(trifluoromethyl)hexahydropyrimidine-5-carboxylate
    Song, Xiao-Ping
    Li, Gong-Chun
    Wu, Chang-Zeng
    Yang, Feng-Ling
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O1083 - U151
  • [7] rac-Ethyl 2-hydroxy-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3,4,5,6,7,8-hexahydro-2H-chromene-3-carboxylate
    Maharramov, Abel M.
    Ismiev, Arif I.
    Rashidov, Bahruz A.
    Askerov, Rizvan K.
    Potekhin, Konstantin A.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O99 - +
  • [8] Synthesis, structural, spectroscopical and DFT studies on third order NLO crystal: Ethyl-5‑hydroxy‑4-(2-hydroxyphenyl)-2-oxo-6-(trifluoromethyl) hexahydropyrimidine5-carboxylate (EHOTHPC)
    Sathiya, S.
    Senthilkumar, M.
    Umarani, P.
    Journal of Molecular Structure, 2022, 1224
  • [9] rac-Ethyl4-hydroxy-4-trifluoromethyl-6-(2,4,5-trimethoxyphenyl)-2-thio-1,3-diazinane-5-carboxylate
    Li, Yong-Qiang
    Ju, Zhi-Yu
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O3092 - +
  • [10] Ethyl 6-(4-fluorophenyl)-4-hydroxy-2-oxo-4-trifluoromethyl-1,3-diazinane-5-carboxylate monohydrate
    Li, Gong-Chun
    Wu, Chang-Zeng
    Guo, Li-Li
    Yang, Feng-Ling
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O1704 - U846