Paucity and discordance of neutralising antibody responses to SARS-CoV-2 VOCs in vaccinated immunodeficient patients and health-care workers in the UK

被引：15

作者：

Nadesalingam, Angalee ^{[1
]}

Cantoni, Diego ^{[2
]}

Wells, David A. ^{[1
]}

Aguinam, Ernest T. ^{[1
]}

Ferrari, Matteo ^{[1
]}

Smith, Peter ^{[1
]}

Chan, Andrew ^{[1
]}

Carnell, George

Ohlendorf, Luis ^{[1
]}

Einhauser, Sebastian ^{[4
]}

George, Charlotte ^{[1
]}

Wagner, Ralf ^{[3
,4
]}

Temperton, Nigel ^{[2
]}

Castillo-Olivares, Javier ^{[1
]}

Baxendale, Helen ^{[5
]}

Heeney, Jonathan L. ^{[1
]}

机构：

[1] Univ Cambridge, Lab Viral Zoonot, Cambridge CB3 OES, England

[2] Univ Kent, Medway Sch Pharm, Viral Pseudotype Unit, Medway, England

[3] Univ Regensburg, Inst Clin Microbiol & Hyg, Regensburg, Germany

[4] Univ Regensburg, Inst Med Microbiol & Hyg, Regensburg, Germany

[5] Royal Papworth NHS Fdn Trust, Clin Immunol Dept, Cambridge, England

来源：

LANCET MICROBE | 2021年 / 2卷 / 09期

基金：

英国生物技术与生命科学研究理事会; 美国国家卫生研究院;

关键词：

D O I：

10.1016/S2666-5247(21)00157-9

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

引用

页码：E416 / E418

页数：3

共 13 条

[1] Effectiveness of the BNT162b2 Covid-19 Vaccine against the B.1.1.7 and B.1.351 Variants [J].

Abu-Raddad, Laith J. ;

Chemaitelly, Hiam ;

Butt, Adeel A. .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (02) :187-189

[2] Neutralizing Antibodies Correlate with Protection from SARS-CoV-2 in Humans during a Fishery Vessel Outbreak with a High Attack Rate [J].

Addetia, Amin ;

Crawford, Katharine H. D. ;

Dingens, Adam ;

Zhu, Haiying ;

Roychoudhury, Pavitra ;

Huang, Meei-Li ;

Jerome, Keith R. ;

Bloom, Jesse D. ;

Greninger, Alexander L. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2020, 58 (11)

[3] Risk of mortality in patients infected with SARS-CoV-2 variant of concern 202012/1: matched cohort study [J].

Challen, Robert ;

Brooks-Pollock, Ellen ;

Read, Jonathan M. ;

Dyson, Louise ;

Tsaneva-Atanasova, Krasimira ;

Danon, Leon .

BMJ-BRITISH MEDICAL JOURNAL, 2021, 372

[4]

Davies NG, 2021, NATURE, V593, P270, DOI [10.1101/2021.02.01.21250959, 10.1038/s41586-021-03426-1]

[5] Antibody evasion by the P.1 strain of SARS-CoV-2 [J].

Dejnirattisai, Wanwisa ;

Zhou, Daming ;

Supasa, Piyada ;

Liu, Chang ;

Mentzer, Alexander J. ;

Ginn, Helen M. ;

Zhao, Yuguang ;

Duyvesteyn, Helen M. E. ;

Tuekprakhon, Aekkachai ;

Nutalai, Rungtiwa ;

Wang, Beibei ;

Lopez-Camacho, Cesar ;

Slon-Campos, Jose ;

Walter, Thomas S. ;

Skelly, Donal ;

Clemens, Sue Ann Costa ;

Naveca, Felipe Gomes ;

Nascimento, Valdinete ;

Nascimento, Fernanda ;

da Costa, Cristiano Fernandes ;

Resende, Paola Cristina ;

Pauvolid-Correa, Alex ;

Siqueira, Marilda M. ;

Dold, Christina ;

Levin, Robert ;

Dong, Tao ;

Pollard, Andrew J. ;

Knight, Julian C. ;

Crook, Derrick ;

Lambe, Teresa ;

Clutterbuck, Elizabeth ;

Bibi, Sagida ;

Flaxman, Amy ;

Bittaye, Mustapha ;

Belij-Rammerstorfer, Sandra ;

Gilbert, Sarah C. ;

Carroll, Miles W. ;

Klenerman, Paul ;

Barnes, Eleanor ;

Dunachie, Susanna J. ;

Paterson, Neil G. ;

Williams, Mark A. ;

Hall, David R. ;

Hulswit, Ruben J. G. ;

Bowden, Thomas A. ;

Fry, Elizabeth E. ;

Mongkolsapaya, Juthathip ;

Ren, Jingshan ;

Stuart, David, I ;

Screaton, Gavin R. .

CELL, 2021, 184 (11) :2939-+

[6]

Di Genova C, 2020, FIGSHARE, DOI [10.6084/m9. figshare.13502580.v2, DOI 10.6084/M9.FIGSHARE.13502580.V2]

[7]

Freitas ARR, EMERGENCE NOVEL SARS

[8] COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study [J].

Hall, Victoria Jane ;

Foulkes, Sarah ;

Saei, Ayoub ;

Andrews, Nick ;

Oguti, Blanche ;

Charlett, Andre ;

Wellington, Edgar ;

Stowe, Julia ;

Gillson, Natalie ;

Atti, Ana ;

Islam, Jasmin ;

Karagiannis, Ioannis ;

Munro, Katie ;

Khawam, Jameel ;

Chand, Meera A. ;

Brown, Colin S. ;

Ramsay, Mary ;

Lopez-Bernal, Jamie ;

Hopkins, Susan .

LANCET, 2021, 397 (10286) :1725-1735

[9] Covid-19: Infections fell by 65% after first dose of AstraZeneca or Pfizer vaccine, data show [J].

Iacobucci, Gareth .

BMJ-BRITISH MEDICAL JOURNAL, 2021, 373 :n1068

[10] SARS-CoV-2 evolution during treatment of chronic infection [J].

Kemp, Steven A. ;

Collier, Dami A. ;

Datir, Rawlings P. ;

Ferreira, Isabella A. T. M. ;

Gayed, Salma ;

Jahun, Aminu ;

Hosmillo, Myra ;

Rees-Spear, Chloe ;

Mlcochova, Petra ;

Lumb, Ines Ushiro ;

Roberts, David J. ;

Chandra, Anita ;

Temperton, Nigel ;

Sharrocks, Katherine ;

Blane, Elizabeth ;

Modis, Yorgo ;

Leigh, Kendra E. ;

Briggs, John A. G. ;

van Gils, Marit J. ;

Smith, Kenneth G. C. ;

Bradley, John R. ;

Smith, Chris ;

Doffinger, Rainer ;

Ceron-Gutierrez, Lourdes ;

Barcenas-Morales, Gabriela ;

Pollock, David D. ;

Goldstein, Richard A. ;

Smielewska, Anna ;

Skittrall, Jordan P. ;

Gouliouris, Theodore ;

Goodfellow, Ian G. ;

Gkrania-Klotsas, Effrossyni ;

Illingworth, Christopher J. R. ;

McCoy, Laura E. ;

Gupta, Ravindra K. .

NATURE, 2021, 592 (7853) :277-+

← 1 2 →