Eosinophilic Granulomatosis with Polyangiitis

被引:2
|
作者
Shukla, Ratnakar [1 ]
Kandikatla, Ashwini [2 ,3 ]
Nadkarni, NitinJ [4 ]
Patil, Anant [5 ]
机构
[1] All India Inst Med Sci, Dept Dermatol, Gorakhpur, Uttar Pradesh, India
[2] HBT Med Coll, Dept Dermatol, Mumbai, Maharashtra, India
[3] Dr RN Cooper Municipal Gen Hosp, Mumbai, Maharashtra, India
[4] Dr DY Patil Med Coll, Dept Dermatol, Mumbai, Maharashtra, India
[5] Dr DY Patil Med Coll, Dept Pharmacol, Mumbai, Maharashtra, India
关键词
Churg-Strauss syndrome; eosinophilia; eosinophilic granulomatosis with polyangiitis; P-antineutrophil cytoplasmic antibody;
D O I
10.4103/ijabmr.ijabmr_528_21
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Eosinophilic granulomatosis with polyangiitis also known as Churg-Strauss syndrome or allergic granulomatosis and angiitis is an extremely rare systemic necrotizing vasculitis that affects small-to-medium-sized vessels. Here, we report a case of a 58-year-old man presenting with painful swelling of bilateral lower limbs with multiple well-defined erosions on lower legs and dorsum of the foot with a few of them showing brownish crusts and with slight watery discharge and a few with raw areas. The patient is a known case of bronchial asthma. Histopathology of foot and face lesion shows inflammatory cell infiltrate predominantly comprising of eosinophils, small- and medium-sized blood vessels are thickened. P-antineutrophil cytoplasmic antibody positivity was seen. Thus, on the basis of positive findings which satisfy the criteria for eosinophilic granulomatosis with polyangiitis, we diagnosed this as a case of eosinophilic granulomatosis with polyangiitis, and for rarity of this case, we would like to report it.
引用
收藏
页码:148 / 150
页数:3
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