机构:
All India Inst Med Sci, Dept Dermatol, Gorakhpur, Uttar Pradesh, IndiaAll India Inst Med Sci, Dept Dermatol, Gorakhpur, Uttar Pradesh, India
Shukla, Ratnakar
[1
]
Kandikatla, Ashwini
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机构:
HBT Med Coll, Dept Dermatol, Mumbai, Maharashtra, India
Dr RN Cooper Municipal Gen Hosp, Mumbai, Maharashtra, IndiaAll India Inst Med Sci, Dept Dermatol, Gorakhpur, Uttar Pradesh, India
Kandikatla, Ashwini
[2
,3
]
Nadkarni, NitinJ
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机构:
Dr DY Patil Med Coll, Dept Dermatol, Mumbai, Maharashtra, IndiaAll India Inst Med Sci, Dept Dermatol, Gorakhpur, Uttar Pradesh, India
Nadkarni, NitinJ
[4
]
Patil, Anant
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机构:
Dr DY Patil Med Coll, Dept Pharmacol, Mumbai, Maharashtra, IndiaAll India Inst Med Sci, Dept Dermatol, Gorakhpur, Uttar Pradesh, India
Patil, Anant
[5
]
机构:
[1] All India Inst Med Sci, Dept Dermatol, Gorakhpur, Uttar Pradesh, India
[2] HBT Med Coll, Dept Dermatol, Mumbai, Maharashtra, India
[3] Dr RN Cooper Municipal Gen Hosp, Mumbai, Maharashtra, India
[4] Dr DY Patil Med Coll, Dept Dermatol, Mumbai, Maharashtra, India
[5] Dr DY Patil Med Coll, Dept Pharmacol, Mumbai, Maharashtra, India
Churg-Strauss syndrome;
eosinophilia;
eosinophilic granulomatosis with polyangiitis;
P-antineutrophil cytoplasmic antibody;
D O I:
10.4103/ijabmr.ijabmr_528_21
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Eosinophilic granulomatosis with polyangiitis also known as Churg-Strauss syndrome or allergic granulomatosis and angiitis is an extremely rare systemic necrotizing vasculitis that affects small-to-medium-sized vessels. Here, we report a case of a 58-year-old man presenting with painful swelling of bilateral lower limbs with multiple well-defined erosions on lower legs and dorsum of the foot with a few of them showing brownish crusts and with slight watery discharge and a few with raw areas. The patient is a known case of bronchial asthma. Histopathology of foot and face lesion shows inflammatory cell infiltrate predominantly comprising of eosinophils, small- and medium-sized blood vessels are thickened. P-antineutrophil cytoplasmic antibody positivity was seen. Thus, on the basis of positive findings which satisfy the criteria for eosinophilic granulomatosis with polyangiitis, we diagnosed this as a case of eosinophilic granulomatosis with polyangiitis, and for rarity of this case, we would like to report it.
机构:
Ohio State Univ, Dept Internal Med, Div Dermatol, Columbus, OH 43210 USAOhio State Univ, Dept Internal Med, Div Dermatol, Columbus, OH 43210 USA
Korman, Abraham M.
Chung, Catherine G.
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机构:
Ohio State Univ, Dept Internal Med, Div Dermatol, Columbus, OH 43210 USA
Ohio State Univ, Dept Pathol, Columbus, OH 43210 USAOhio State Univ, Dept Internal Med, Div Dermatol, Columbus, OH 43210 USA