Comparison of the osteogenic differentiation capacity of adipose tissue derived mesenchymal stem cells from humans and rats

被引：2

作者：

Erden Tayhan, Secil ^{[1
]}

Tasdemir, Seyma ^{[2
]}

Deliloglu Gurhan, Saime Ismet ^{[2
]}

Mir, Erol ^{[3
]}

机构：

[1] Gaziosmanpasa Univ, Fac Engn & Nat Sci, Dept Bioengn, Tokat, Turkey

[2] Ege Univ, Dept Bioengn, Fac Engn, Izmir, Turkey

[3] Celal Bayar Univ, Dept Pediat Surg, Fac Med, Manisa, Turkey

来源：

TURKISH JOURNAL OF BIOLOGY | 2016年 / 40卷 / 05期

关键词：

Osteogenic differentiation; mesenchymal stem cell; adipose tissue; human; rat; STROMAL CELLS; BONE-MARROW; IDENTIFICATION;

D O I：

10.3906/biy-1507-128

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mesenchymal stem cells (MSCs) can be found in many types of adult tissues such as the bone marrow, adipose, placenta, liver, and periosteum. Recently, adipose tissue-derived MSCs (ADMSCs) have become one the most preferred MSC types because of their fast proliferation rate, abundance, and high plasticity for variable cell types. It is known that ADMSCs are able to differentiate into various cells, including osteoblasts, so they are quite promising for orthopedic clinical trials. The present study aimed to compare the osteogenic differentiation conditions of MSCs from human adipose tissue (hADMSC) and those of MSCs from rat adipose tissue (rADMSC). Therefore, differentiation experiments with five different media and two (human and rat) ADMSC types were performed and the mineralization responses of hADMSCs and rADMSCs were different.

引用

页码：1090 / 1095

页数：6

共 16 条

[1] Isolation, characterization and osteogenic differentiation of adipose-derived stem cells: from small to large animal models [J].

Arrigoni, Elena ;

Lopa, Silvia ;

de Girolamo, Laura ;

Stanco, Deborah ;

Brini, Anna T. .

CELL AND TISSUE RESEARCH, 2009, 338 (03) :401-411

[2] Random/aligned electrospun PCL/PCL-collagen nanofibrous membranes: comparison of neural differentiation of rat AdMSCs and BMSCs [J].

Capkin, Merve ;

Cakmak, Soner ;

Kurt, Feyzan Ozdal ;

Gumusderelioglu, Menemse ;

Sen, B. Hakan ;

Turk, B. Tugba ;

Deliloglu-Gurhan, S. Ismet .

BIOMEDICAL MATERIALS, 2012, 7 (04)

[3] Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells [J].

Colter, DC ;

Sekiya, I ;

Prockop, DJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (14) :7841-7845

[4] Resveratrol effect on osteogenic differentiation of rat and human adipose derived stem cells in a 3-D culture environment [J].

Dosier, Christopher R. ;

Erdman, Christopher P. ;

Park, Jung Hwa ;

Schwartz, Zui ;

Boyan, Barbara D. ;

Guldberg, Robert E. .

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 2012, 11 :112-122

[5] Human stem cell delivery for treatment of large segmental bone defects [J].

Dupont, Kenneth M. ;

Sharma, Kapil ;

Stevens, Hazel Y. ;

Boerckel, Joel D. ;

Garcia, Andres J. ;

Guldberg, Robert E. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (08) :3305-3310

[6] Influence of cell culture media conditions on the osteogenic differentiation of cord blood-derived mesenchymal stem cells [J].

Hildebrandt, Cornelia ;

Bueth, Heiko ;

Thielecke, Hagen .

ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER, 2009, 191 (01) :23-32

[7] Osteogenic differentiation of human adipose tissue-derived stromal cells (hASCs) in a porous three-dimensional scaffold [J].

Lee, Jung Ho ;

Rhie, Jong Won ;

Oh, Deul Young ;

Ahn, Sang Tae .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 370 (03) :456-460

[8] Comparative analysis of human mesenchymal stem cells from bone marrow and adipose tissue under xeno-free conditions for cell therapy [J].

Li, Chun-yu ;

Wu, Xiao-yun ;

Tong, Jia-bei ;

Yang, Xin-xin ;

Zhao, Jing-li ;

Zheng, Quan-fu ;

Zhao, Guo-bin ;

Ma, Zhi-jie .

STEM CELL RESEARCH & THERAPY, 2015, 6

[9] Identification of common pathways mediating differentiation of bone marrow- and adipose tissue-derived human mesenchymal stem cells into three mesenchymal lineages [J].

Liu, Tong Ming ;

Martina, Monique ;

Hutmacher, Dietmar W. ;

Hui, James Hoi Po ;

Lee, Eng Hin ;

Lim, Bing .

STEM CELLS, 2007, 25 (03) :750-760

[10]

Ni Yong-wei, 2009, Beijing Da Xue Xue Bao Yi Xue Ban, V41, P95

← 1 2 →