'Sinus node' dysfunction associated with left atrial isomerism

Introduction The eterotaxic syndromes encompass two main anatomic pictures: left and right atrial isomerism. They cause a distortion of the atria anatomy that may involve the conduction tissue. The prognosis is related to the severity of the intracardiac-associated defects. Case report We describe the case of a patient suffering from asymptomatic 'sinus' bradycardia since childhood, who was referred for pacemaker implantation, in which the diagnosis of left atrial isomerism was made. Conclusion The present paper may provide new insights on the clinical course of arrhythmic disorders, in particular among patients with congenital heart disease.