Phosphorylation of CARMA1:: The link(er) to NF-κB activation

被引：37

作者：

Rueda, D ^{[1
]}

Thome, M ^{[1
]}

机构：

[1] Univ Lausanne, Dept Biochem, BIL Biomed Res Ctr, CH-1066 Epalinges, Switzerland

来源：

IMMUNITY | 2005年 / 23卷 / 06期

关键词：

D O I：

10.1016/j.immuni.2005.11.007

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Antigen receptor-induced NF-KB activation depends on receptor-proximal and -distal signaling events. Two papers in this issue of Immunity demonstrate that PKC-dependent phosphorylation of CARMA1 is the critical molecular link that controls the activation of the IKK signalosome and NF-KB.

引用

页码：551 / 553

页数：3

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