Osmotic Pump Drug Delivery Systems-A Comprehensive Review

被引：40

作者：

Almoshari, Yosif ^{[1
]}

机构：

[1] Jazan Univ, Coll Pharm, Dept Pharmaceut, Jazan 45142, Saudi Arabia

来源：

PHARMACEUTICALS | 2022年 / 15卷 / 11期

关键词：

osmotic pump; osmosis; controlled release system; novel drug delivery system; osmotic pressure; CONTROLLED-RELEASE; DESIGN; FORMULATION; TABLET; NIFEDIPINE; MECHANISM;

D O I：

10.3390/ph15111430

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

In the last couple of years, novel drug delivery systems (NDDS) have attracted much attention in the food and pharmaceutical industries. NDDS is a broad term that encompasses many dosage forms, one of which is osmotic pumps. Osmotic pumps are considered to be the most reliable source of controlled drug delivery, both in humans and in animals. These pumps are osmotically controlled and release active agents through osmotic pressure. To a large extent, drug release from such a system is independent of gastric fluids. Based on such unique properties and advantages, osmotic pumps have made their mark on the pharmaceutical industry. This review summarizes the available osmotic devices for implantation and osmotic tablets for oral administration.

引用

页数：16

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