Recurrence after Radiotherapy for Gastric Mucosa-associated Lymphoid Tissue (MALT) Lymphoma with Trisomy 18

被引：8

作者：

Ishikawa, Hisashi ^{[1
]}

Iwamuro, Masaya ^{[1
,2
]}

Okada, Hiroyuki ^{[3
]}

Hori, Keisuke ^{[1
]}

Kita, Masahide ^{[1
]}

Kawano, Seiji ^{[3
]}

Kawahara, Yoshiro ^{[3
]}

Tanaka, Takehiro ^{[4
]}

Kondo, Eisei ^{[5
]}

Yoshino, Tadashi ^{[6
]}

Yamamoto, Kazuhide ^{[1
]}

机构：

[1] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Gastroenterol & Hepatol, Okayama 7008530, Japan

[2] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Mol Hepatol, Okayama 7008530, Japan

[3] Okayama Univ Hosp, Dept Endoscopy, Okayama, Japan

[4] Okayama Univ Hosp, Dept Pathol, Okayama, Japan

[5] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Gen Med, Okayama 7008530, Japan

[6] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol, Okayama 7008530, Japan

来源：

INTERNAL MEDICINE | 2015年 / 54卷 / 08期

关键词：

extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue; MALT lymphoma; gastric lymphoma; trisomy; 18; B-CELL LYMPHOMA; HELICOBACTER-PYLORI ERADICATION; GENETIC ABERRATIONS; RADIATION-THERAPY; FREQUENCIES;

D O I：

10.2169/internalmedicine.54.3784

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 36-year-old Japanese woman presented with extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the stomach. The gastric lesions only partially improved after eradication therapy for Helicobacter pylori. A fluorescence in situ hybridization analysis revealed no fusion genes of API2-MALT1, although trisomy of chromosome 18 was identified. Radiation therapy was initiated to treat the gastric lymphoma lesions, resulting in complete remission. However, MALT lymphoma recurred in the stomach 16 months later. This case indicates that intensive follow-up is required for MALT lymphoma associated with chromosomal aberrations in order to detect early relapse.

引用

收藏

页码：911 / 916

页数：6

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