A Novel Sandwich-type Electrochemical Aptasensor Based on GR-3D Au and Aptamer-AuNPs-HRP for Sensitive Detection of Oxytetracycline

被引：2

作者：

Liu, Su ^{[1
]}

Wang, Yu ^{[2
]}

Xu, Wei ^{[3
]}

Leng, Xueqi ^{[1
]}

Wang, Hongzhi ^{[3
]}

Guo, Yuna ^{[3
]}

Huang, Jiadong ^{[2
,3
]}

机构：

[1] Univ Jinan, Coll Resources & Environm, Jinan 250022, Shandong, Peoples R China

[2] Univ Jinan, Coll Biol Sci & Technol, Jinan 250022, Shandong, Peoples R China

[3] Univ Jinan, Coll Chem & Chem Engn, Key Lab Chem Sensing & Anal Univ Shandong, Jinan 250022, Shandong, Peoples R China

来源：

BIOSENSORS 2016 | 2017年 / 27卷

关键词：

Graphene-gold nanostructure; Horseradish peroxidase; Electrochemical aptasensor; Sandwich-type; Oxytetracycline; KANAMYCIN; NANOPARTICLES;

D O I：

10.1016/j.protcy.2017.04.066

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A novel sandwich-type electrochemical aptasensor has been fabricated and applied for sensitive and selective detection of antibiotic oxytetracycline (OTC). This sensor was based on graphene-three dimensional nanostructure gold nanocomposite (GR-3D Au) and aptamer-AuNPs-horseradish peroxidase (HRP) nanoprobes as signal amplification. The aptamer and HRP modified Au nanoparticles provide high affinity and ultrasensitive electrochemical probe with excellent specificity for OTC. (C) 2017 Published by Elsevier Ltd.

引用

页码：151 / 152

页数：2

共 5 条

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